Utilizing harmonization and common surveillance methods to consolidate 4 cohorts: The western Alaska tribal collaborative for health (WATCH) study

Kathryn R. Koller, Abbie W. Wolfe, Jesse S. Metzger, Melissa A. Austin, Scarlett E. Hopkins, Cristiane Kaufmann, Stacey E. Jolly, Sven O.E. Ebbesson, Jason G. Umans, Barbara V. Howard, Bert Boyer

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background. According to health status reports, chronic disease prevalence appears to be rising in western Alaska Native (AN) people, and accurate population-based data are needed. Four cohort studies of western AN people were conducted in the Norton Sound and Yukon-Kuskokwim regions, but none have been large enough to allow reliable estimates of rates of chronic diseases and evaluate their risk factors. Objective. In this article, the methods used to combine 4 major cohort studies of rural western AN people are described and the benefits and challenges encountered in combining data and standardizing surveillance methods for these studies are discussed. Design. Tribal permission was obtained for each cohort study and the consolidated study. Data from baseline exams were directly combined or harmonized into new variables. Common surveillance methods were developed and implemented to identify incidence and risk factors for cardiovascular disease (CVD) events and type 2 diabetes. Results. A cohort of 4,569 western AN participants (2,116 men and 2,453 women), aged 18-95 years, was established to study CVD and diabetes prevalence. Prospective surveillance data over an average 6.7-year follow-up can now be used to study CVD and diabetes incidence and associated risk factors in a subset of 2,754 western AN participants (1,218 men and 1,536 women) who consented to initial surveillance. Conclusions. The combined cohort provides statistical power to examine incidence rates and risk factors for CVD and diabetes and allows for analyses by geographic region. The data can be used to develop intervention programmes in these populations and others.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalInternational journal of circumpolar health
Volume72
Issue number1
DOIs
StatePublished - May 2 2013
Externally publishedYes

Fingerprint

harmonization
surveillance
Disease
Cardiovascular Diseases
chronic illness
Health
health
Cohort Studies
incidence
Incidence
Yukon Territory
Chronic Disease
Population Control
Type 2 Diabetes Mellitus
Health Status
health status
Alaska Natives
event
Population

Keywords

  • Alaska native
  • Cardiovascular disease
  • Cohort study
  • Risk factors
  • Statistical power
  • Type 2 diabetes

ASJC Scopus subject areas

  • Epidemiology
  • Health(social science)
  • Public Health, Environmental and Occupational Health

Cite this

Utilizing harmonization and common surveillance methods to consolidate 4 cohorts : The western Alaska tribal collaborative for health (WATCH) study. / Koller, Kathryn R.; Wolfe, Abbie W.; Metzger, Jesse S.; Austin, Melissa A.; Hopkins, Scarlett E.; Kaufmann, Cristiane; Jolly, Stacey E.; Ebbesson, Sven O.E.; Umans, Jason G.; Howard, Barbara V.; Boyer, Bert.

In: International journal of circumpolar health, Vol. 72, No. 1, 02.05.2013, p. 1-7.

Research output: Contribution to journalArticle

Koller, Kathryn R. ; Wolfe, Abbie W. ; Metzger, Jesse S. ; Austin, Melissa A. ; Hopkins, Scarlett E. ; Kaufmann, Cristiane ; Jolly, Stacey E. ; Ebbesson, Sven O.E. ; Umans, Jason G. ; Howard, Barbara V. ; Boyer, Bert. / Utilizing harmonization and common surveillance methods to consolidate 4 cohorts : The western Alaska tribal collaborative for health (WATCH) study. In: International journal of circumpolar health. 2013 ; Vol. 72, No. 1. pp. 1-7.
@article{c2d866695a77427e9a9662f581d21b3a,
title = "Utilizing harmonization and common surveillance methods to consolidate 4 cohorts: The western Alaska tribal collaborative for health (WATCH) study",
abstract = "Background. According to health status reports, chronic disease prevalence appears to be rising in western Alaska Native (AN) people, and accurate population-based data are needed. Four cohort studies of western AN people were conducted in the Norton Sound and Yukon-Kuskokwim regions, but none have been large enough to allow reliable estimates of rates of chronic diseases and evaluate their risk factors. Objective. In this article, the methods used to combine 4 major cohort studies of rural western AN people are described and the benefits and challenges encountered in combining data and standardizing surveillance methods for these studies are discussed. Design. Tribal permission was obtained for each cohort study and the consolidated study. Data from baseline exams were directly combined or harmonized into new variables. Common surveillance methods were developed and implemented to identify incidence and risk factors for cardiovascular disease (CVD) events and type 2 diabetes. Results. A cohort of 4,569 western AN participants (2,116 men and 2,453 women), aged 18-95 years, was established to study CVD and diabetes prevalence. Prospective surveillance data over an average 6.7-year follow-up can now be used to study CVD and diabetes incidence and associated risk factors in a subset of 2,754 western AN participants (1,218 men and 1,536 women) who consented to initial surveillance. Conclusions. The combined cohort provides statistical power to examine incidence rates and risk factors for CVD and diabetes and allows for analyses by geographic region. The data can be used to develop intervention programmes in these populations and others.",
keywords = "Alaska native, Cardiovascular disease, Cohort study, Risk factors, Statistical power, Type 2 diabetes",
author = "Koller, {Kathryn R.} and Wolfe, {Abbie W.} and Metzger, {Jesse S.} and Austin, {Melissa A.} and Hopkins, {Scarlett E.} and Cristiane Kaufmann and Jolly, {Stacey E.} and Ebbesson, {Sven O.E.} and Umans, {Jason G.} and Howard, {Barbara V.} and Bert Boyer",
year = "2013",
month = "5",
day = "2",
doi = "10.3402/ijch.v72i0.20572",
language = "English (US)",
volume = "72",
pages = "1--7",
journal = "International Journal of Circumpolar Health",
issn = "1239-9744",
publisher = "Co-Action Publishing",
number = "1",

}

TY - JOUR

T1 - Utilizing harmonization and common surveillance methods to consolidate 4 cohorts

T2 - The western Alaska tribal collaborative for health (WATCH) study

AU - Koller, Kathryn R.

AU - Wolfe, Abbie W.

AU - Metzger, Jesse S.

AU - Austin, Melissa A.

AU - Hopkins, Scarlett E.

AU - Kaufmann, Cristiane

AU - Jolly, Stacey E.

AU - Ebbesson, Sven O.E.

AU - Umans, Jason G.

AU - Howard, Barbara V.

AU - Boyer, Bert

PY - 2013/5/2

Y1 - 2013/5/2

N2 - Background. According to health status reports, chronic disease prevalence appears to be rising in western Alaska Native (AN) people, and accurate population-based data are needed. Four cohort studies of western AN people were conducted in the Norton Sound and Yukon-Kuskokwim regions, but none have been large enough to allow reliable estimates of rates of chronic diseases and evaluate their risk factors. Objective. In this article, the methods used to combine 4 major cohort studies of rural western AN people are described and the benefits and challenges encountered in combining data and standardizing surveillance methods for these studies are discussed. Design. Tribal permission was obtained for each cohort study and the consolidated study. Data from baseline exams were directly combined or harmonized into new variables. Common surveillance methods were developed and implemented to identify incidence and risk factors for cardiovascular disease (CVD) events and type 2 diabetes. Results. A cohort of 4,569 western AN participants (2,116 men and 2,453 women), aged 18-95 years, was established to study CVD and diabetes prevalence. Prospective surveillance data over an average 6.7-year follow-up can now be used to study CVD and diabetes incidence and associated risk factors in a subset of 2,754 western AN participants (1,218 men and 1,536 women) who consented to initial surveillance. Conclusions. The combined cohort provides statistical power to examine incidence rates and risk factors for CVD and diabetes and allows for analyses by geographic region. The data can be used to develop intervention programmes in these populations and others.

AB - Background. According to health status reports, chronic disease prevalence appears to be rising in western Alaska Native (AN) people, and accurate population-based data are needed. Four cohort studies of western AN people were conducted in the Norton Sound and Yukon-Kuskokwim regions, but none have been large enough to allow reliable estimates of rates of chronic diseases and evaluate their risk factors. Objective. In this article, the methods used to combine 4 major cohort studies of rural western AN people are described and the benefits and challenges encountered in combining data and standardizing surveillance methods for these studies are discussed. Design. Tribal permission was obtained for each cohort study and the consolidated study. Data from baseline exams were directly combined or harmonized into new variables. Common surveillance methods were developed and implemented to identify incidence and risk factors for cardiovascular disease (CVD) events and type 2 diabetes. Results. A cohort of 4,569 western AN participants (2,116 men and 2,453 women), aged 18-95 years, was established to study CVD and diabetes prevalence. Prospective surveillance data over an average 6.7-year follow-up can now be used to study CVD and diabetes incidence and associated risk factors in a subset of 2,754 western AN participants (1,218 men and 1,536 women) who consented to initial surveillance. Conclusions. The combined cohort provides statistical power to examine incidence rates and risk factors for CVD and diabetes and allows for analyses by geographic region. The data can be used to develop intervention programmes in these populations and others.

KW - Alaska native

KW - Cardiovascular disease

KW - Cohort study

KW - Risk factors

KW - Statistical power

KW - Type 2 diabetes

UR - http://www.scopus.com/inward/record.url?scp=84877156608&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84877156608&partnerID=8YFLogxK

U2 - 10.3402/ijch.v72i0.20572

DO - 10.3402/ijch.v72i0.20572

M3 - Article

C2 - 23671836

AN - SCOPUS:84877156608

VL - 72

SP - 1

EP - 7

JO - International Journal of Circumpolar Health

JF - International Journal of Circumpolar Health

SN - 1239-9744

IS - 1

ER -