TY - JOUR
T1 - Utility of the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) in patients with end-stage liver disease awaiting liver transplant
AU - Mooney, Scott
AU - Hasssanein, Tarek I.
AU - Hilsabeck, Robin C.
AU - Ziegler, Elizabeth A.
AU - Carlson, Meghan
AU - Maron, Leeza M.
AU - Perry, William
PY - 2007/2
Y1 - 2007/2
N2 - Cognitive impairment is common among patients with end-stage liver disease (ESLD). This study examined cognitive dysfunction in patients with ESLD using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Method: 66 patients with ESLD awaiting liver transplant were recruited. Patients were evaluated with the RBANS, Peabody Picture Vocabulary Test-Revised, and Beck Depression Inventory-II. Results: Patients with ESLD uniformly performed below expectations on all RBANS index scores compared to the healthy normative sample (all p's < .0001) and they also displayed a "subcortical" pattern of cognitive performance (p < .0001). Performances on RBANS attention, language, immediate memory, and total index scores were correlated with education and ethnicity (r's range = |.32-.57|; p's < .01). There was no association between performance on any of the RBANS index scores or subtests and ESLD patient characteristics. In summary, the RBANS appears to adequately characterize known patterns of cognitive dysfunction in ESLD patients.
AB - Cognitive impairment is common among patients with end-stage liver disease (ESLD). This study examined cognitive dysfunction in patients with ESLD using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). Method: 66 patients with ESLD awaiting liver transplant were recruited. Patients were evaluated with the RBANS, Peabody Picture Vocabulary Test-Revised, and Beck Depression Inventory-II. Results: Patients with ESLD uniformly performed below expectations on all RBANS index scores compared to the healthy normative sample (all p's < .0001) and they also displayed a "subcortical" pattern of cognitive performance (p < .0001). Performances on RBANS attention, language, immediate memory, and total index scores were correlated with education and ethnicity (r's range = |.32-.57|; p's < .01). There was no association between performance on any of the RBANS index scores or subtests and ESLD patient characteristics. In summary, the RBANS appears to adequately characterize known patterns of cognitive dysfunction in ESLD patients.
KW - End stage liver disease
KW - Repeatable Battery for the Assessment of Neuropsychological Status
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U2 - 10.1016/j.acn.2006.12.005
DO - 10.1016/j.acn.2006.12.005
M3 - Article
C2 - 17280813
AN - SCOPUS:33847611508
SN - 0887-6177
VL - 22
SP - 175
EP - 186
JO - Archives of Clinical Neuropsychology
JF - Archives of Clinical Neuropsychology
IS - 2
ER -