Using patient-reportable clinical history factors to predict myocardial infarction

Samuel J. Wang, Lucila Ohno-Machado, Hamish S.F. Fraser, R. Lee Kennedy

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Using a derivation data set of 1253 patients, we built several logistic regression and neural network models to estimate the likelihood of myocardial infarction based upon patient-reportable clinical history factors only. The best performing logistic regression model and neural network model had C-indices of 0.8444 and 0.8503, respectively, when validated on an independent data set of 500 patients. We conclude that both logistic regression and neural network models can be built that successfully predict the probability of myocardial infarction based on patient-reportable history factors alone. These models could have important utility in applications outside of a hospital setting when objective diagnostic test information is not yet be available. Copyright (C) 2001 Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)1-13
Number of pages13
JournalComputers in Biology and Medicine
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2001

Keywords

  • Artificial intelligence
  • Decision support techniques
  • Logistic models
  • Myocardial infarction
  • Neural networks (computer)
  • Regression analysis

ASJC Scopus subject areas

  • Computer Science Applications
  • Health Informatics

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