Use of the Non-Pneumatic Anti-Shock Garment (NASG) for Life-Threatening Obstetric Hemorrhage: A Cost-Effectiveness Analysis in Egypt and Nigeria

Tori Sutherland, Janelle Downing, Suellen Miller, David M. Bishai, Elizabeth Butrick, Mohamed M.F. Fathalla, Mohammed Mourad-Youssif, Oladosu Ojengbede, David Nsima, James G. Kahn

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objective:To assess the cost-effectiveness of a non-pneumatic anti-shock garment (NASG) for obstetric hemorrhage in tertiary hospitals in Egypt and Nigeria.Methods:We combined published data from pre-intervention/NASG-intervention clinical trials with costs from study sites. For each country, we used observed proportions of initial shock level (mild: mean arterial pressure [MAP] >60 mmHg; severe: MAP ≤60 mmHg) to define a standard population of 1,000 women presenting in shock. We examined three intervention scenarios: no women in shock receive the NASG, only women in severe shock receive the NASG, and all women in shock receive the NASG. Clinical data included frequencies of adverse health outcomes (mortality, severe morbidity, severe anemia), and interventions to manage bleeding (uterotonics, blood transfusions, hysterectomies). Costs (in 2010 international dollars) included the NASG, training, and clinical interventions. We compared costs and disability-adjusted life years (DALYs) across the intervention scenarios.Results:For 1000 women presenting in shock, providing the NASG to those in severe shock results in decreased mortality and morbidity, which averts 357 DALYs in Egypt and 2,063 DALYs in Nigeria. Differences in use of interventions result in net savings of $9,489 in Egypt (primarily due to reduced transfusions) and net costs of $6,460 in Nigeria, with a cost per DALY averted of $3.13. Results of providing the NASG for women in mild shock has smaller and uncertain effects due to few clinical events in this data set.Conclusion:Using the NASG for women in severe shock resulted in markedly improved health outcomes (2-2.9 DALYs averted per woman, primarily due to reduced mortality), with net savings or extremely low cost per DALY averted. This suggests that in resource-limited settings, the NASG is a very cost-effective intervention for women in severe hypovolemic shock. The effects of the NASG for mild shock are less certain.

Original languageEnglish (US)
Article numbere62282
JournalPloS one
Volume8
Issue number4
DOIs
StatePublished - Apr 30 2013
Externally publishedYes

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Obstetrics
Clothing
Egypt
cost effectiveness
Cost effectiveness
Nigeria
clothing
Cost-Benefit Analysis
hemorrhage
Shock
disability-adjusted life year
Hemorrhage
Costs
Quality-Adjusted Life Years
Health
Costs and Cost Analysis
morbidity
hypovolemic shock
hysterectomy
Blood

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Use of the Non-Pneumatic Anti-Shock Garment (NASG) for Life-Threatening Obstetric Hemorrhage : A Cost-Effectiveness Analysis in Egypt and Nigeria. / Sutherland, Tori; Downing, Janelle; Miller, Suellen; Bishai, David M.; Butrick, Elizabeth; Fathalla, Mohamed M.F.; Mourad-Youssif, Mohammed; Ojengbede, Oladosu; Nsima, David; Kahn, James G.

In: PloS one, Vol. 8, No. 4, e62282, 30.04.2013.

Research output: Contribution to journalArticle

Sutherland, T, Downing, J, Miller, S, Bishai, DM, Butrick, E, Fathalla, MMF, Mourad-Youssif, M, Ojengbede, O, Nsima, D & Kahn, JG 2013, 'Use of the Non-Pneumatic Anti-Shock Garment (NASG) for Life-Threatening Obstetric Hemorrhage: A Cost-Effectiveness Analysis in Egypt and Nigeria', PloS one, vol. 8, no. 4, e62282. https://doi.org/10.1371/journal.pone.0062282
Sutherland, Tori ; Downing, Janelle ; Miller, Suellen ; Bishai, David M. ; Butrick, Elizabeth ; Fathalla, Mohamed M.F. ; Mourad-Youssif, Mohammed ; Ojengbede, Oladosu ; Nsima, David ; Kahn, James G. / Use of the Non-Pneumatic Anti-Shock Garment (NASG) for Life-Threatening Obstetric Hemorrhage : A Cost-Effectiveness Analysis in Egypt and Nigeria. In: PloS one. 2013 ; Vol. 8, No. 4.
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