Use of minors as bone marrow donors: Current attitude and management - A survey of 56 pediatric transplantation centers

Wah Chan Ka Wah Chan, J. L. Gajewski, D. Supkis, R. Pentz, R. Champlin, W. A. Bleyer

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Objective: To determine the current attitude about the use of minors as bone morrow donors in pediatric bone morrow transplantation (BMT) centers in North America. Study design: A questionnaire was mailed to 70 North American BMT centers. The questionnaire asked for opinions on a number of ethical and clinical issues pertaining to the use of minors as marrow donors. A case history was included and respondents were asked to check all appropriate answers listed in the survey. Results: Fifty-six (80%) of 70 centers responded. There was general consensus on many issues. Pediatricians endorse the validity of parental consent, even in potentially controversial situations. Most are prepared to extract marrow from young (about 6 months of age) infants and are willing to use the same donor more than once. There is general approval of performing BMT with experimental protocols, and the projected outcome of BMT does not affect the decision to use a minor as a morrow donor. There is less consensus regarding the optimal management of minors donating a large volume of bone marrow. Conclusion: This survey shows a fairly consistent attitude among pediatric BMT centers about the use of minors as marrow donors. The actual management of such donors was not evaluated in detail and requires further study.

Original languageEnglish (US)
Pages (from-to)644-648
Number of pages5
JournalJournal of Pediatrics
Volume128
Issue number5 I
DOIs
StatePublished - 1996
Externally publishedYes

Fingerprint

Minors
Bone Transplantation
Transplantation
Bone Marrow
Tissue Donors
Pediatrics
Consensus
Parental Consent
North America
Ethics
Surveys and Questionnaires
Bone and Bones

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Use of minors as bone marrow donors : Current attitude and management - A survey of 56 pediatric transplantation centers. / Ka Wah Chan, Wah Chan; Gajewski, J. L.; Supkis, D.; Pentz, R.; Champlin, R.; Bleyer, W. A.

In: Journal of Pediatrics, Vol. 128, No. 5 I, 1996, p. 644-648.

Research output: Contribution to journalArticle

Ka Wah Chan, Wah Chan ; Gajewski, J. L. ; Supkis, D. ; Pentz, R. ; Champlin, R. ; Bleyer, W. A. / Use of minors as bone marrow donors : Current attitude and management - A survey of 56 pediatric transplantation centers. In: Journal of Pediatrics. 1996 ; Vol. 128, No. 5 I. pp. 644-648.
@article{7bc404bb369042369e70c8adae412e3a,
title = "Use of minors as bone marrow donors: Current attitude and management - A survey of 56 pediatric transplantation centers",
abstract = "Objective: To determine the current attitude about the use of minors as bone morrow donors in pediatric bone morrow transplantation (BMT) centers in North America. Study design: A questionnaire was mailed to 70 North American BMT centers. The questionnaire asked for opinions on a number of ethical and clinical issues pertaining to the use of minors as marrow donors. A case history was included and respondents were asked to check all appropriate answers listed in the survey. Results: Fifty-six (80{\%}) of 70 centers responded. There was general consensus on many issues. Pediatricians endorse the validity of parental consent, even in potentially controversial situations. Most are prepared to extract marrow from young (about 6 months of age) infants and are willing to use the same donor more than once. There is general approval of performing BMT with experimental protocols, and the projected outcome of BMT does not affect the decision to use a minor as a morrow donor. There is less consensus regarding the optimal management of minors donating a large volume of bone marrow. Conclusion: This survey shows a fairly consistent attitude among pediatric BMT centers about the use of minors as marrow donors. The actual management of such donors was not evaluated in detail and requires further study.",
author = "{Ka Wah Chan}, {Wah Chan} and Gajewski, {J. L.} and D. Supkis and R. Pentz and R. Champlin and Bleyer, {W. A.}",
year = "1996",
doi = "10.1016/S0022-3476(96)80129-6",
language = "English (US)",
volume = "128",
pages = "644--648",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "5 I",

}

TY - JOUR

T1 - Use of minors as bone marrow donors

T2 - Current attitude and management - A survey of 56 pediatric transplantation centers

AU - Ka Wah Chan, Wah Chan

AU - Gajewski, J. L.

AU - Supkis, D.

AU - Pentz, R.

AU - Champlin, R.

AU - Bleyer, W. A.

PY - 1996

Y1 - 1996

N2 - Objective: To determine the current attitude about the use of minors as bone morrow donors in pediatric bone morrow transplantation (BMT) centers in North America. Study design: A questionnaire was mailed to 70 North American BMT centers. The questionnaire asked for opinions on a number of ethical and clinical issues pertaining to the use of minors as marrow donors. A case history was included and respondents were asked to check all appropriate answers listed in the survey. Results: Fifty-six (80%) of 70 centers responded. There was general consensus on many issues. Pediatricians endorse the validity of parental consent, even in potentially controversial situations. Most are prepared to extract marrow from young (about 6 months of age) infants and are willing to use the same donor more than once. There is general approval of performing BMT with experimental protocols, and the projected outcome of BMT does not affect the decision to use a minor as a morrow donor. There is less consensus regarding the optimal management of minors donating a large volume of bone marrow. Conclusion: This survey shows a fairly consistent attitude among pediatric BMT centers about the use of minors as marrow donors. The actual management of such donors was not evaluated in detail and requires further study.

AB - Objective: To determine the current attitude about the use of minors as bone morrow donors in pediatric bone morrow transplantation (BMT) centers in North America. Study design: A questionnaire was mailed to 70 North American BMT centers. The questionnaire asked for opinions on a number of ethical and clinical issues pertaining to the use of minors as marrow donors. A case history was included and respondents were asked to check all appropriate answers listed in the survey. Results: Fifty-six (80%) of 70 centers responded. There was general consensus on many issues. Pediatricians endorse the validity of parental consent, even in potentially controversial situations. Most are prepared to extract marrow from young (about 6 months of age) infants and are willing to use the same donor more than once. There is general approval of performing BMT with experimental protocols, and the projected outcome of BMT does not affect the decision to use a minor as a morrow donor. There is less consensus regarding the optimal management of minors donating a large volume of bone marrow. Conclusion: This survey shows a fairly consistent attitude among pediatric BMT centers about the use of minors as marrow donors. The actual management of such donors was not evaluated in detail and requires further study.

UR - http://www.scopus.com/inward/record.url?scp=0029917625&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029917625&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(96)80129-6

DO - 10.1016/S0022-3476(96)80129-6

M3 - Article

C2 - 8627436

AN - SCOPUS:0029917625

VL - 128

SP - 644

EP - 648

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 5 I

ER -