Use of a temperature-sensitive mutant to define the biological effects of the p210^BCR-ABL tyrosine kinase on proliferation of a factor-dependent murine myeloid cell line

Medicine & Life Sciences

• Myeloid Cells 100%
• Protein-Tyrosine Kinases 89%
• Temperature 70%
• Cell Line 57%
• Interleukin-3 28%
• Tyrosine 22%
• Intercellular Signaling Peptides and Proteins 19%
• Phosphotransferases 18%
• Amino Acids 17%
• Chromosomes, Human, Pair 22 16%
• Chromosomes, Human, Pair 9 16%
• Philadelphia Chromosome 15%
• Proteins 13%
• Amino Acid Substitution 13%
• Leukemia, Myelogenous, Chronic, BCR-ABL Positive 12%
• Oncogenes 11%
• Exons 10%
• Cell Death 9%
• Phosphorylation 8%
• Mutation 6%