Use of a simple clinical tool for airway assessment to predict adverse pregnancy outcomes

Amanda S. Trudell, Judette M. Louis, Methodius G. Tuuli, Aaron B. Caughey, Anthony O. Odibo, Alison G. Cahill

Research output: Contribution to journalArticlepeer-review


Objective Obstructive sleep apnea (OSA) is a risk factor for adverse perinatal outcomes. We aimed to test the hypothesis that maternal Mallampati class (MC), as a marker for OSA, is associated with adverse perinatal outcomes. Study Design We performed a retrospective secondary analysis of a prospective cohort of term births (≥ 37 weeks). Fetal anomalies and aneuploidy were excluded. Primary outcome was small for gestational age (SGA). Secondary outcomes included preeclampsia, neonatal cord arterial blood gas pH < 7.10 and < 7.05, base excess <-8 and <-12 mEq/L. Outcomes were compared between mothers with low MC airways and high MC airways using logistic regression. Results A total of 1,823 women met the inclusion criteria. No significant differences were found in the risk of SGA (adjusted odds ratio [aOR] 0.9, 95% confidence interval [CI] 0.6-1.2), preeclampsia (aOR 1.2, 95% CI 0.8-1.9) or neonatal acidemia (aOR 0.8, 95% CI 0.3-2.0), between high and low MC. Conclusion High MC is not associated with adverse perinatal outcomes.

Original languageEnglish (US)
Pages (from-to)257-262
Number of pages6
JournalAmerican journal of perinatology
Issue number3
StatePublished - Feb 2015


  • Mallampati
  • OSA
  • obstructive sleep apnea
  • sleep disordered breathing
  • small for gestational age

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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