Uroepithelial carcinoma in association with cyclophosphamide ingestion

Eugene Fuchs, R. Kay, R. Poole, John Barry, H. D. Pearse

Research output: Contribution to journalArticle

32 Scopus citations


The association of daily oral cyclophosphamide with the development of transitional cell carcinoma or squamous cell carcinoma of the bladder has been documented. We report the first 2 cases of transitional cell carcinoma of the renal pelvis and an additional 4 cases of transitional cell carcinoma of the bladder following cyclophosphamide ingestion. Patients who have been taking daily oral cyclophosphamide for a prolonged period should have excretory urography, cystoscopy and bladder mucosal biopsies performed as part of a cancer surveillance protocol.

Original languageEnglish (US)
Pages (from-to)544-545
Number of pages2
JournalJournal of Urology
Issue number4
Publication statusPublished - 1981


ASJC Scopus subject areas

  • Urology

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