Uptake and distribution of radioactive selenium in cataractous rat lens

T. R. Shearer, R. S. Anderson, J. L. Britton

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

A cataractous dose of sodium selenite tagged with 75Se was injected into 10-day-old pups. It was shown for the first time that 75Se accumulated in the soluble and insoluble proteins of the lens. 75Se was not concentrated in the nuclear cataract. Interaction of selenium with structural or enzymatic proteins of the lens may be an important step in the mechanism of selenite induced cataract.

Original languageEnglish (US)
Pages (from-to)561-564
Number of pages4
JournalCurrent Eye Research
Volume2
Issue number8
StatePublished - 1982

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Fingerprint Dive into the research topics of 'Uptake and distribution of radioactive selenium in cataractous rat lens'. Together they form a unique fingerprint.

Cite this