A cataractous dose of sodium selenite tagged with 75Se was injected into 10-day-old pups. It was shown for the first time that 75Se accumulated in the soluble and insoluble proteins of the lens. 75Se was not concentrated in the nuclear cataract. Interaction of selenium with structural or enzymatic proteins of the lens may be an important step in the mechanism of selenite induced cataract.
|Original language||English (US)|
|Number of pages||4|
|Journal||Current Eye Research|
|State||Published - 1982|
ASJC Scopus subject areas
- Sensory Systems
- Cellular and Molecular Neuroscience