Updates in Pediatric Glioma Pathology

Research output: Contribution to journalReview articlepeer-review

Abstract

Gliomas are a diverse group of primary central nervous system tumors with astrocytic, oligodendroglial, and/or ependymal features and are an important cause of morbidity/mortality in pediatric patients. Glioma classification relies on integrating tumor histology with key molecular alterations. This approach can help establish a diagnosis, guide treatment, and determine prognosis. New categories of pediatric glioma have been recognized in recent years, due to increasing application of molecular profiling in brain tumors. The aim of this review is to alert pediatric pathologists to emerging diagnostic concepts in pediatric glioma neuropathology, emphasizing the incorporation of molecular features into diagnostic practice.

Original languageEnglish (US)
Pages (from-to)801-816
Number of pages16
JournalSurgical Pathology Clinics
Volume13
Issue number4
DOIs
StatePublished - Dec 2020

Keywords

  • Astrocytoma
  • Glioblastoma
  • Glioma
  • Molecular profiling
  • Pediatric

ASJC Scopus subject areas

  • Surgery
  • Pathology and Forensic Medicine

Fingerprint

Dive into the research topics of 'Updates in Pediatric Glioma Pathology'. Together they form a unique fingerprint.

Cite this