Universal tuberculosis screening in pregnancy

Nadav Schwartz, Sarah A. Wagner, Sean M. Keeler, Julian Mierlak, David E. Seubert, Aaron Caughey

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

We reviewed our practice of universal tuberculosis (TB) screening in an at-risk pregnant population with regards to utility and patient compliance. The Gouverneur Healthcare Services prenatal database was analyzed for compliance with TB screening. Age, ethnicity, country of origin, and education level were also analyzed. Of 4049 patients, 95.0% were compliant with their purified protein derivative (PPD) testing. Universal screening identified 1935 (50.4%) PPD+ patients, with chest X-rays (CXR) available for 95.1%. Only one patient had a CXR consistent with active TB, although sputum testing was negative for acid-fast bacilli. Asian women were more likely to be PPD-compliant (adjusted odds ratio [aOR]: 4.94, 95% confidence interval [CI]: 2.34 to 10.45). Similarly, PPD+ Asian women were more likely to be compliant with CXR (aOR: 12.67, 95% CI: 3.44 to 46.7). U.S.-born women were significantly less likely to be compliant with PPD (aOR: 0.44, 95% CI: 0.30 to 0.64) or with CXR (aOR: 0.22, 95% CI: 0.08 to 0.61). Universal prenatal TB screening is associated with excellent compliance rates and is an effective way to identify a high prevalence of latent TB, but not active disease.

Original languageEnglish (US)
Pages (from-to)447-452
Number of pages6
JournalAmerican Journal of Perinatology
Volume26
Issue number6
DOIs
StatePublished - Jun 2009
Externally publishedYes

Fingerprint

Tuberculosis
Pregnancy
Thorax
Odds Ratio
X-Rays
Confidence Intervals
Proteins
Latent Tuberculosis
Patient Compliance
Sputum
Prenatal Diagnosis
Bacillus
Databases
Delivery of Health Care
Education
Acids

Keywords

  • Latent tuberculosis
  • PPD
  • Tuberculosis screening

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Schwartz, N., Wagner, S. A., Keeler, S. M., Mierlak, J., Seubert, D. E., & Caughey, A. (2009). Universal tuberculosis screening in pregnancy. American Journal of Perinatology, 26(6), 447-452. https://doi.org/10.1055/s-0029-1214244

Universal tuberculosis screening in pregnancy. / Schwartz, Nadav; Wagner, Sarah A.; Keeler, Sean M.; Mierlak, Julian; Seubert, David E.; Caughey, Aaron.

In: American Journal of Perinatology, Vol. 26, No. 6, 06.2009, p. 447-452.

Research output: Contribution to journalArticle

Schwartz, N, Wagner, SA, Keeler, SM, Mierlak, J, Seubert, DE & Caughey, A 2009, 'Universal tuberculosis screening in pregnancy', American Journal of Perinatology, vol. 26, no. 6, pp. 447-452. https://doi.org/10.1055/s-0029-1214244
Schwartz N, Wagner SA, Keeler SM, Mierlak J, Seubert DE, Caughey A. Universal tuberculosis screening in pregnancy. American Journal of Perinatology. 2009 Jun;26(6):447-452. https://doi.org/10.1055/s-0029-1214244
Schwartz, Nadav ; Wagner, Sarah A. ; Keeler, Sean M. ; Mierlak, Julian ; Seubert, David E. ; Caughey, Aaron. / Universal tuberculosis screening in pregnancy. In: American Journal of Perinatology. 2009 ; Vol. 26, No. 6. pp. 447-452.
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