Abstract
We report a case in which unilateral testicular enlargement was the only presenting sign in 21-hydroxylase deficiency of the 'acquired' or adult onset type. Measurement of plasma 17-hydroxyprogesterone throughout 24 hours revealed marked elevations, mostly between 0400 and 0700 hours. However, this steroid increased more than 18-fold 30 minutes following adrenocorticotropic hormone administration, confirming the diagnosis. Glucocorticoid therapy corrected the testicular enlargement. Inapparent 21-hydroxylase deficiency is a medically treatable cause of testicular enlargement that can be diagnosed by measurement of plasma 17-hydroxyprogesterone during a 30-minute adrenocorticotropic hormone stimulation test.
Original language | English (US) |
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Pages (from-to) | 127-128 |
Number of pages | 2 |
Journal | Journal of Urology |
Volume | 126 |
Issue number | 1 |
DOIs | |
State | Published - 1981 |
Externally published | Yes |
ASJC Scopus subject areas
- Urology