Unemployment in chronic airflow obstruction around the world: Results from the BOLD study

Rune Grønseth, Marta Erdal, Wan C. Tan, Daniel O. Obaseki, Andre F.S. Amaral, Thorarinn Gislason, Sanjay K. Juvekar, Parvaiz A. Koul, Michael Studnicka, Sundeep Salvi, Peter Burney, A (Sonia) Buist, William M. Vollmer, Ane Johannessen

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We aimed to examine associations between chronic airflow obstruction (CAO) and unemployment across the world. Cross-sectional data from 26 sites in the Burden of Obstructive Lung Disease (BOLD) study were used to analyse effects of CAO on unemployment. Odds ratios for unemployment in subjects aged 40-65 years were estimated using a multilevel mixed-effects generalised linear model with study site as random effect. Site-by-site heterogeneity was assessed using individual participant data meta-analyses. Out of 18 710 participants, 11.3% had CAO. The ratio of unemployed subjects with CAO divided by subjects without CAO showed large site discrepancies, although these were no longer significant after adjusting for age, sex, smoking and education. The site-adjusted odds ratio (95% CI) for unemployment was 1.79 (1.41-2.27) for CAO cases, decreasing to 1.43 (1.14-1.79) after adjusting for sociodemographic factors, comorbidities and forced vital capacity. Of other covariates that were associated with unemployment, age and education were important risk factors in high-income sites (4.02 (3.53-4.57) and 3.86 (2.80-5.30), respectively), while female sex was important in low- to middle-income sites (3.23 (2.66-3.91)). In the global BOLD study, CAO was associated with increased levels of unemployment, even after adjusting for sociodemographic factors, comorbidities and lung function.

Original languageEnglish (US)
Article number00499
JournalEuropean Respiratory Journal
Volume50
Issue number3
DOIs
StatePublished - Sep 1 2017

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Obstructive Lung Diseases
Unemployment
Chronic Obstructive Pulmonary Disease
Comorbidity
Odds Ratio
Sex Education
Vital Capacity
Meta-Analysis
Linear Models
Smoking
Education
Lung

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Grønseth, R., Erdal, M., Tan, W. C., Obaseki, D. O., Amaral, A. F. S., Gislason, T., ... Johannessen, A. (2017). Unemployment in chronic airflow obstruction around the world: Results from the BOLD study. European Respiratory Journal, 50(3), [00499]. https://doi.org/10.1183/13993003.00499-2017

Unemployment in chronic airflow obstruction around the world : Results from the BOLD study. / Grønseth, Rune; Erdal, Marta; Tan, Wan C.; Obaseki, Daniel O.; Amaral, Andre F.S.; Gislason, Thorarinn; Juvekar, Sanjay K.; Koul, Parvaiz A.; Studnicka, Michael; Salvi, Sundeep; Burney, Peter; Buist, A (Sonia); Vollmer, William M.; Johannessen, Ane.

In: European Respiratory Journal, Vol. 50, No. 3, 00499, 01.09.2017.

Research output: Contribution to journalArticle

Grønseth, R, Erdal, M, Tan, WC, Obaseki, DO, Amaral, AFS, Gislason, T, Juvekar, SK, Koul, PA, Studnicka, M, Salvi, S, Burney, P, Buist, AS, Vollmer, WM & Johannessen, A 2017, 'Unemployment in chronic airflow obstruction around the world: Results from the BOLD study', European Respiratory Journal, vol. 50, no. 3, 00499. https://doi.org/10.1183/13993003.00499-2017
Grønseth, Rune ; Erdal, Marta ; Tan, Wan C. ; Obaseki, Daniel O. ; Amaral, Andre F.S. ; Gislason, Thorarinn ; Juvekar, Sanjay K. ; Koul, Parvaiz A. ; Studnicka, Michael ; Salvi, Sundeep ; Burney, Peter ; Buist, A (Sonia) ; Vollmer, William M. ; Johannessen, Ane. / Unemployment in chronic airflow obstruction around the world : Results from the BOLD study. In: European Respiratory Journal. 2017 ; Vol. 50, No. 3.
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