Ultrastructural study of selenite-induced nuclear cataracts

N. J. Russell, J. E. Royland, E. L. McCawley, T. R. Shearer

Research output: Contribution to journalArticle

10 Scopus citations

Abstract

The formation of the selenite-induced cataract was investigated by examining the ultrastructure of the cataract with transmission electron microscopy (TEM). A lacy, or honeycomb, appearance of the nuclear cataract seen by light microscopy was resolved by TEM to be due to the aggregation or precipitation of cytoplasmic material. Despite severe intracellular changes the fibers retained their close apposition to one another. These results are consistent with the hypothesis that a major lesion in selenite-induced nuclear cataracts is the formation of insoluble cytoplasmic aggregates.

Original languageEnglish (US)
Pages (from-to)751-757
Number of pages7
JournalInvestigative Ophthalmology and Visual Science
Volume25
Issue number6
StatePublished - Jan 1 1984

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ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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