Ultrahigh-speed ultrahigh-resolution adaptive optics: Optical coherence tomography system for in-vivo small animal retinal imaging

Yifan Jian, Jing Xu, Robert J. Zawadzki, Marinko V. Sarunic

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Small animal models of human retinal diseases are a critical component of vision research. In this report, we present an ultrahigh-resolution ultrahigh-speed adaptive optics optical coherence tomography (AO-OCT) system for small animal retinal imaging (mouse, fish, etc.). We adapted our imaging system to different types of small animals in accordance with the optical properties of their eyes. Results of AO-OCT images of small animal retinas acquired with AO correction are presented. Cellular structures including nerve fiber bundles, capillary networks and detailed double-cone photoreceptors are visualized.

Original languageEnglish (US)
Title of host publicationOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
DOIs
StatePublished - May 22 2013
Externally publishedYes
EventOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII - San Francisco, CA, United States
Duration: Feb 4 2013Feb 6 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8571
ISSN (Print)1605-7422

Other

OtherOptical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
CountryUnited States
CitySan Francisco, CA
Period2/4/132/6/13

Fingerprint

Adaptive optics
Optical tomography
Optical Coherence Tomography
Optical resolving power
adaptive optics
animals
Animals
tomography
Imaging techniques
Retinal Cone Photoreceptor Cells
nerve fibers
Retinal Diseases
photoreceptors
animal models
retina
fishes
Cellular Structures
Nerve Fibers
bundles
mice

Keywords

  • Adaptive Optics
  • Optical Coherence Tomography
  • Small Animal

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Jian, Y., Xu, J., Zawadzki, R. J., & Sarunic, M. V. (2013). Ultrahigh-speed ultrahigh-resolution adaptive optics: Optical coherence tomography system for in-vivo small animal retinal imaging. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII [85711R] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8571). https://doi.org/10.1117/12.2006652

Ultrahigh-speed ultrahigh-resolution adaptive optics : Optical coherence tomography system for in-vivo small animal retinal imaging. / Jian, Yifan; Xu, Jing; Zawadzki, Robert J.; Sarunic, Marinko V.

Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. 2013. 85711R (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 8571).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jian, Y, Xu, J, Zawadzki, RJ & Sarunic, MV 2013, Ultrahigh-speed ultrahigh-resolution adaptive optics: Optical coherence tomography system for in-vivo small animal retinal imaging. in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII., 85711R, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, San Francisco, CA, United States, 2/4/13. https://doi.org/10.1117/12.2006652
Jian Y, Xu J, Zawadzki RJ, Sarunic MV. Ultrahigh-speed ultrahigh-resolution adaptive optics: Optical coherence tomography system for in-vivo small animal retinal imaging. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. 2013. 85711R. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2006652
Jian, Yifan ; Xu, Jing ; Zawadzki, Robert J. ; Sarunic, Marinko V. / Ultrahigh-speed ultrahigh-resolution adaptive optics : Optical coherence tomography system for in-vivo small animal retinal imaging. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. 2013. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).
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