UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease

K. Gregg, Morgan Hakki, D. R. Kaul

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

We present a case of foscarnet (FOS) resistance arising from a UL54 mutation after a short duration of FOS exposure, which has not been previously described in a stem cell transplant recipient, to our knowledge. We discuss the use of FOS to treat other viral infections and the implications this may have for the development of resistance mutations and treatment of cytomegalovirus disease.

Original languageEnglish (US)
Pages (from-to)320-323
Number of pages4
JournalTransplant Infectious Disease
Volume16
Issue number2
DOIs
StatePublished - 2014

Fingerprint

Foscarnet
Hematopoietic Stem Cells
Cytomegalovirus
Transplants
Mutation
Virus Diseases
Stem Cells
Transplant Recipients
Therapeutics

Keywords

  • Cytomegalovirus
  • E756K mutation
  • Foscarnet
  • Resistance
  • UL54

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases
  • Medicine(all)

Cite this

UL54 foscarnet mutation in an hematopoietic stem cell transplant recipient with cytomegalovirus disease. / Gregg, K.; Hakki, Morgan; Kaul, D. R.

In: Transplant Infectious Disease, Vol. 16, No. 2, 2014, p. 320-323.

Research output: Contribution to journalArticle

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