Type D SRV-2 virus-specific CD8+ and CD4- CD8- T cells that regulate virus-induced T cell proliferation in Celebes macaques.

A. Malley, N. Pangares, S. K. Mayo, M. Zeleny-Pooley, J. V. Torres, E. Benjamin, M. K. Axthelm

    Research output: Contribution to journalArticle

    Abstract

    These studies defined SRV-2 envelope peptides 96-102, 127-152, and 233-249 as T cell epitopes that induce significant T cell proliferation. Peripheral blood lymphocytes of Celebes macaques (Macaca nigra) exposed to SRV-2 and currently virus- antibody+, cultured with SRV-2 virus show strongly suppressed T cell responses and have two immunoregulatory T cell populations.

    Original languageEnglish (US)
    Pages (from-to)80-85
    Number of pages6
    JournalJournal of medical primatology
    Volume22
    Issue number2-3
    StatePublished - Jan 1 1993

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    ASJC Scopus subject areas

    • Animal Science and Zoology
    • veterinary(all)

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