Type 2 diabetes mellitus and 20 year incidence of periodontitis and tooth loss

Monik Jimenez, Frank B. Hu, Miguel Marino, Yi Li, Kaumudi J. Joshipura

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Aims: The objective of this study was to evaluate the prospective associations between type 2 diabetes mellitus (T2DM) and the risk of periodontitis and tooth loss. Methods: 35,247 male participants of the Health Professionals Follow-Up Study who were dentate, free of periodontitis and cancer at baseline, were followed from 1986 to 2006. Data on self-reported diabetes, periodontitis, tooth loss and potential confounders were collected at baseline and biennially through mailed questionnaires. The multivariable adjusted relationships between diabetes and first report of periodontitis and tooth loss were estimated using time-varying Cox models. Results: There were 3009 incident self-reported periodontitis and 10,017 tooth loss events over 591,941 person-years. Men with T2DM showed a 29% (HR = 1.29; 95% CI: 1.13-1.47) increased risk of periodontitis compared to those without, when adjusted for age, race, smoking, BMI, fruit and vegetable intake, physical activity, alcohol consumption and dental profession. Men with T2DM with total fruit and vegetable intake. <median were 49% as likely to report incident periodontitis compared to those without T2DM (HR = 1.49; 95% CI: 1.23-1.80; p-value for interaction = 0.03). The multivariable adjusted risk of tooth loss was 1.10 (95% CI: 1.02-1.18). Conclusions: Type 2 diabetes mellitus was associated with a significantly greater risk of self-reported periodontitis.

Original languageEnglish (US)
Pages (from-to)494-500
Number of pages7
JournalDiabetes Research and Clinical Practice
Volume98
Issue number3
DOIs
StatePublished - Dec 2012
Externally publishedYes

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Tooth Loss
Periodontitis
Type 2 Diabetes Mellitus
Incidence
Vegetables
Fruit
Proportional Hazards Models
Alcohol Drinking
Tooth
Smoking
Exercise
Health

Keywords

  • Epidemiology
  • Oral disease
  • Periodontitis
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Endocrinology

Cite this

Type 2 diabetes mellitus and 20 year incidence of periodontitis and tooth loss. / Jimenez, Monik; Hu, Frank B.; Marino, Miguel; Li, Yi; Joshipura, Kaumudi J.

In: Diabetes Research and Clinical Practice, Vol. 98, No. 3, 12.2012, p. 494-500.

Research output: Contribution to journalArticle

Jimenez, Monik ; Hu, Frank B. ; Marino, Miguel ; Li, Yi ; Joshipura, Kaumudi J. / Type 2 diabetes mellitus and 20 year incidence of periodontitis and tooth loss. In: Diabetes Research and Clinical Practice. 2012 ; Vol. 98, No. 3. pp. 494-500.
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