Tubal patency during the menstrual cycle and during treatment with hormonal contraceptives: A pilot study in women

Jeffrey Jensen, Eva Patil, Jacqueline Seguin, Amy Thurmond

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background Hysterosalpingram (HSG) evaluation of tubal patency is typically performed in the follicular phase, but data to support this timing are lacking. Purpose To determine whether menstrual cycle phase or hormonal treatments affect observation of tubal patency during HSG. Material and Methods Ten participants underwent repeated HSG examinations: during the follicular and luteal phase of a natural menstrual cycle; 30 days following continuous administration of a combined oral contraceptive (COC); and 30 days after an intramuscular injection of depo medroxyprogesterone (DMPA) acetate. Participants with tubal blockade following DMPA had a fifth HSG 30 days following a second course of COCs. The primary outcome was tubal patency. Results All 10 participants demonstrated bilateral tubal patency (BTP) on at least one HSG examination during the study. One participant showed bilateral functional occlusion (FO) during the follicular phase examination, but BTP with the luteal phase, COC cycle, and DMPA exams. One participant with BTP discontinued participation and nine completed the COC HSG exam with BTP in seven, and one each with bilateral or unilateral FO. Seven participants completed the DMPA HSG with BTP in six and unilateral FO in one; BTP was seen in the final HSG after restarting the COC. Conclusion This pilot study supports the luteal phase of natural cycles as the optimum time for evaluation of tubal patency. The occurrence of functional occlusion of the fallopian tube on HSG examination performed during the follicular phase and following contraceptive steroid treatment supports a role of hormonal action on the utero-tubal junction.

Original languageEnglish (US)
Pages (from-to)1020-1025
Number of pages6
JournalActa Radiologica
Volume58
Issue number8
DOIs
StatePublished - Aug 1 2017

Fingerprint

Contraceptives, Oral, Combined
Follicular Phase
Menstrual Cycle
Contraceptive Agents
Luteal Phase
Medroxyprogesterone Acetate
Fallopian Tubes
Intramuscular Injections
Therapeutics
Steroids
Observation
N,N-dimethyl-4-anisidine

Keywords

  • Fallopian tubes
  • Hysterosalpingography
  • menstrual cycle
  • oral contraception
  • tubal sterilization

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

Cite this

Tubal patency during the menstrual cycle and during treatment with hormonal contraceptives : A pilot study in women. / Jensen, Jeffrey; Patil, Eva; Seguin, Jacqueline; Thurmond, Amy.

In: Acta Radiologica, Vol. 58, No. 8, 01.08.2017, p. 1020-1025.

Research output: Contribution to journalArticle

Jensen, Jeffrey ; Patil, Eva ; Seguin, Jacqueline ; Thurmond, Amy. / Tubal patency during the menstrual cycle and during treatment with hormonal contraceptives : A pilot study in women. In: Acta Radiologica. 2017 ; Vol. 58, No. 8. pp. 1020-1025.
@article{3c2b5f95148e414dbd4cb30abb8fe9f7,
title = "Tubal patency during the menstrual cycle and during treatment with hormonal contraceptives: A pilot study in women",
abstract = "Background Hysterosalpingram (HSG) evaluation of tubal patency is typically performed in the follicular phase, but data to support this timing are lacking. Purpose To determine whether menstrual cycle phase or hormonal treatments affect observation of tubal patency during HSG. Material and Methods Ten participants underwent repeated HSG examinations: during the follicular and luteal phase of a natural menstrual cycle; 30 days following continuous administration of a combined oral contraceptive (COC); and 30 days after an intramuscular injection of depo medroxyprogesterone (DMPA) acetate. Participants with tubal blockade following DMPA had a fifth HSG 30 days following a second course of COCs. The primary outcome was tubal patency. Results All 10 participants demonstrated bilateral tubal patency (BTP) on at least one HSG examination during the study. One participant showed bilateral functional occlusion (FO) during the follicular phase examination, but BTP with the luteal phase, COC cycle, and DMPA exams. One participant with BTP discontinued participation and nine completed the COC HSG exam with BTP in seven, and one each with bilateral or unilateral FO. Seven participants completed the DMPA HSG with BTP in six and unilateral FO in one; BTP was seen in the final HSG after restarting the COC. Conclusion This pilot study supports the luteal phase of natural cycles as the optimum time for evaluation of tubal patency. The occurrence of functional occlusion of the fallopian tube on HSG examination performed during the follicular phase and following contraceptive steroid treatment supports a role of hormonal action on the utero-tubal junction.",
keywords = "Fallopian tubes, Hysterosalpingography, menstrual cycle, oral contraception, tubal sterilization",
author = "Jeffrey Jensen and Eva Patil and Jacqueline Seguin and Amy Thurmond",
year = "2017",
month = "8",
day = "1",
doi = "10.1177/0284185116679457",
language = "English (US)",
volume = "58",
pages = "1020--1025",
journal = "Acta Radiologica",
issn = "0284-1851",
publisher = "SAGE Publications Ltd",
number = "8",

}

TY - JOUR

T1 - Tubal patency during the menstrual cycle and during treatment with hormonal contraceptives

T2 - A pilot study in women

AU - Jensen, Jeffrey

AU - Patil, Eva

AU - Seguin, Jacqueline

AU - Thurmond, Amy

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Background Hysterosalpingram (HSG) evaluation of tubal patency is typically performed in the follicular phase, but data to support this timing are lacking. Purpose To determine whether menstrual cycle phase or hormonal treatments affect observation of tubal patency during HSG. Material and Methods Ten participants underwent repeated HSG examinations: during the follicular and luteal phase of a natural menstrual cycle; 30 days following continuous administration of a combined oral contraceptive (COC); and 30 days after an intramuscular injection of depo medroxyprogesterone (DMPA) acetate. Participants with tubal blockade following DMPA had a fifth HSG 30 days following a second course of COCs. The primary outcome was tubal patency. Results All 10 participants demonstrated bilateral tubal patency (BTP) on at least one HSG examination during the study. One participant showed bilateral functional occlusion (FO) during the follicular phase examination, but BTP with the luteal phase, COC cycle, and DMPA exams. One participant with BTP discontinued participation and nine completed the COC HSG exam with BTP in seven, and one each with bilateral or unilateral FO. Seven participants completed the DMPA HSG with BTP in six and unilateral FO in one; BTP was seen in the final HSG after restarting the COC. Conclusion This pilot study supports the luteal phase of natural cycles as the optimum time for evaluation of tubal patency. The occurrence of functional occlusion of the fallopian tube on HSG examination performed during the follicular phase and following contraceptive steroid treatment supports a role of hormonal action on the utero-tubal junction.

AB - Background Hysterosalpingram (HSG) evaluation of tubal patency is typically performed in the follicular phase, but data to support this timing are lacking. Purpose To determine whether menstrual cycle phase or hormonal treatments affect observation of tubal patency during HSG. Material and Methods Ten participants underwent repeated HSG examinations: during the follicular and luteal phase of a natural menstrual cycle; 30 days following continuous administration of a combined oral contraceptive (COC); and 30 days after an intramuscular injection of depo medroxyprogesterone (DMPA) acetate. Participants with tubal blockade following DMPA had a fifth HSG 30 days following a second course of COCs. The primary outcome was tubal patency. Results All 10 participants demonstrated bilateral tubal patency (BTP) on at least one HSG examination during the study. One participant showed bilateral functional occlusion (FO) during the follicular phase examination, but BTP with the luteal phase, COC cycle, and DMPA exams. One participant with BTP discontinued participation and nine completed the COC HSG exam with BTP in seven, and one each with bilateral or unilateral FO. Seven participants completed the DMPA HSG with BTP in six and unilateral FO in one; BTP was seen in the final HSG after restarting the COC. Conclusion This pilot study supports the luteal phase of natural cycles as the optimum time for evaluation of tubal patency. The occurrence of functional occlusion of the fallopian tube on HSG examination performed during the follicular phase and following contraceptive steroid treatment supports a role of hormonal action on the utero-tubal junction.

KW - Fallopian tubes

KW - Hysterosalpingography

KW - menstrual cycle

KW - oral contraception

KW - tubal sterilization

UR - http://www.scopus.com/inward/record.url?scp=85021167393&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85021167393&partnerID=8YFLogxK

U2 - 10.1177/0284185116679457

DO - 10.1177/0284185116679457

M3 - Article

C2 - 27856803

AN - SCOPUS:85021167393

VL - 58

SP - 1020

EP - 1025

JO - Acta Radiologica

JF - Acta Radiologica

SN - 0284-1851

IS - 8

ER -