Tri-modal confocal margin screening for the presence of residual squamous cell carcinoma in Mohs surgical excisions

Anna Bar, Nicholas Snavely, Nathaniel Chen, Steven Jacques, Daniel S. Gareau

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Screening cancer in excision margins may be done with confocal microscopy to save time and cost over the gold standard histopathology (H&E). However, diagnostic accuracy requires sufficient contrast. Reflectance mode enables detection of large (>500um) nodular tumors. Enhanced nuclear contrast with acridine orange fluorescence mode additionally enables detection of tiny (

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8214
DOIs
StatePublished - 2012
EventAdvanced Biomedical and Clinical Diagnostic Systems X - San Francisco, CA, United States
Duration: Jan 22 2012Jan 24 2012

Other

OtherAdvanced Biomedical and Clinical Diagnostic Systems X
CountryUnited States
CitySan Francisco, CA
Period1/22/121/24/12

Fingerprint

Acridine Orange
Confocal microscopy
Early Detection of Cancer
Confocal Microscopy
Tumors
Squamous Cell Carcinoma
margins
Screening
screening
Fluorescence
cancer
Costs and Cost Analysis
Costs
Neoplasms
tumors
microscopy
costs
reflectance
fluorescence
Margins of Excision

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Bar, A., Snavely, N., Chen, N., Jacques, S., & Gareau, D. S. (2012). Tri-modal confocal margin screening for the presence of residual squamous cell carcinoma in Mohs surgical excisions. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8214). [821416] https://doi.org/10.1117/12.909902

Tri-modal confocal margin screening for the presence of residual squamous cell carcinoma in Mohs surgical excisions. / Bar, Anna; Snavely, Nicholas; Chen, Nathaniel; Jacques, Steven; Gareau, Daniel S.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8214 2012. 821416.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bar, A, Snavely, N, Chen, N, Jacques, S & Gareau, DS 2012, Tri-modal confocal margin screening for the presence of residual squamous cell carcinoma in Mohs surgical excisions. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8214, 821416, Advanced Biomedical and Clinical Diagnostic Systems X, San Francisco, CA, United States, 1/22/12. https://doi.org/10.1117/12.909902
Bar A, Snavely N, Chen N, Jacques S, Gareau DS. Tri-modal confocal margin screening for the presence of residual squamous cell carcinoma in Mohs surgical excisions. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8214. 2012. 821416 https://doi.org/10.1117/12.909902
Bar, Anna ; Snavely, Nicholas ; Chen, Nathaniel ; Jacques, Steven ; Gareau, Daniel S. / Tri-modal confocal margin screening for the presence of residual squamous cell carcinoma in Mohs surgical excisions. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8214 2012.
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