Treatment of recurrent metastatic colon cancer in the age of modern adjuvant therapy

Carla Kurkjian, Anthony J. Murgo, Shivaani Kummar

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

The treatment of patients with metastatic colon cancer has evolved tremendously over the past 10 years, with improved overall survival (OS) rates as a result of the advent of several important agents. Following the results of important adjuvant trials, the incorporation of oxaliplatin into the adjuvant setting has significantly increased the disease-free survival and OS rates in patients who undergo curative resection. However, still a significant number of patients will present with recurrent disease after being treated with oxaliplatin-containing chemotherapy regimens. Herein, we present approaches to the chemotherapeutic management of such patients with a review of the literature.

Original languageEnglish (US)
Pages (from-to)321-324
Number of pages4
JournalClinical Colorectal Cancer
Volume7
Issue number5
DOIs
StatePublished - Sep 2008
Externally publishedYes

Keywords

  • Metastasis
  • Oxaliplatin
  • Platinum resistance
  • Recurrence

ASJC Scopus subject areas

  • Oncology
  • Gastroenterology

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