Treatment of pigment epithelial detachments due to age-related macular degeneration with intra-ocular C3F8 injection

Mirjam Gross-Jendroska, Christina Flaxel, Steve D. Schwartz, Frank G. Holz, Fred W. Fitzke, Veit Peter Gabel, Alan C. Bird

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: To flatten pigment epithelial detachments (PED) due to age- related macular degeneration in an attempt to visualize the underlying choroidal neovascularization by fluorescein angiography (FA) and reveal a treatment target. Methods: Nine patients with PED received intravitreal gas injections via the pars plana and postured face down. Fluorescein angiograms were obtained before and after gas injection. In two patients, retinal scotopic sensitivity was also measured. Results: Eight patients demonstrated change in the shape and size of the PED following gas injection. Four patients showed a better delineation of underlying structures on FA. Three patients had focal laser treatment to the newly visible choroidal neovascular complex, but this was successful in only one patient with flattening of the PED. Conclusion: Pigment epithelial detachments can be modified by intravitreal gas injection in some patients, but this treatment did not have a major impact on overall outcome or management.

Original languageEnglish (US)
Pages (from-to)311-317
Number of pages7
JournalAustralian and New Zealand Journal of Ophthalmology
Volume26
Issue number4
StatePublished - Nov 1998
Externally publishedYes

Fingerprint

Intraocular Injections
Macular Degeneration
Gases
Intravitreal Injections
Fluorescein Angiography
Therapeutics
Choroidal Neovascularization
Injections
Temazepam
Fluorescein
Angiography
Lasers

Keywords

  • Age-related macular degeneration
  • Fine-matrix mapping
  • Intravitreal gas injection
  • Pigment epithelial detachments

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Gross-Jendroska, M., Flaxel, C., Schwartz, S. D., Holz, F. G., Fitzke, F. W., Gabel, V. P., & Bird, A. C. (1998). Treatment of pigment epithelial detachments due to age-related macular degeneration with intra-ocular C3F8 injection. Australian and New Zealand Journal of Ophthalmology, 26(4), 311-317.

Treatment of pigment epithelial detachments due to age-related macular degeneration with intra-ocular C3F8 injection. / Gross-Jendroska, Mirjam; Flaxel, Christina; Schwartz, Steve D.; Holz, Frank G.; Fitzke, Fred W.; Gabel, Veit Peter; Bird, Alan C.

In: Australian and New Zealand Journal of Ophthalmology, Vol. 26, No. 4, 11.1998, p. 311-317.

Research output: Contribution to journalArticle

Gross-Jendroska, Mirjam ; Flaxel, Christina ; Schwartz, Steve D. ; Holz, Frank G. ; Fitzke, Fred W. ; Gabel, Veit Peter ; Bird, Alan C. / Treatment of pigment epithelial detachments due to age-related macular degeneration with intra-ocular C3F8 injection. In: Australian and New Zealand Journal of Ophthalmology. 1998 ; Vol. 26, No. 4. pp. 311-317.
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