Treatment of pachyonychia congenita.

Leonard M. Milstone, Philip Fleckman, Sancy A. Leachman, Irene M. Leigh, Amy S. Paller, Maurice A.M. van Steensel, Carl Swartling

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


There are currently no specific treatments for pachyonychia congenita (PC). Available treatments generally are directed at specific manifestations of the disorder, and an effective treatment plan must recognize that different patients are more or less troubled by different manifestations of the disease. Treatment for all aspects of PC has been less than completely satisfactory. Very few studies have compared different approaches to treatment, and fewer still have given longitudinal follow-up of efficacy and patient acceptance. This review is essentially a compilation of anecdotes. It was collected from physicians' reports in the literature, from direct communication with physicians currently following patients with PC and from patients who answered a questionnaire on the Pachyonychia Congenita Project web page (

Original languageEnglish (US)
Pages (from-to)18-20
Number of pages3
JournalThe journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research
Issue number1
StatePublished - Oct 2005
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Molecular Biology
  • Dermatology
  • Cell Biology


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