Treatment of malignant fibrous histiocytoma and atypical fibrous xanthomas with micrographic surgery

M. D. Brown, Neil Swanson

Research output: Contribution to journalArticle

53 Citations (Scopus)

Abstract

Fibrous tumors of the soft tissue are usually benign, but some fibrous neoplasms such as dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrohistiocytoma (MFH) can be very destructive locally with a high recurrence rate after local excision. On occasion, they can metastasize. Previous reports have confirmed the high success rate of Mohs micrographic surgery for the treatment of DFSP, but data have been lacking on the potential benefit of this surgical approach for MFH and AFX tumors. Over the past 6 years, we have treated 17 patients with MFH (20 tumors) and 5 patients with AFX with Mohs micrographic surgery. A retrospective analysis of the surgical results is presented. To date (average 3-year follow-up), all patients contacted are tumor free with only one recurrence; no patient has developed metastatic disease. Our results to date are very encouraging; they lend support to Mohs micrographic surgery as a desired surgical approach for these difficult-to-cure neoplasms.

Original languageEnglish (US)
Pages (from-to)1287-1292
Number of pages6
JournalJournal of Dermatologic Surgery and Oncology
Volume15
Issue number12
StatePublished - 1989
Externally publishedYes

Fingerprint

Xanthomatosis
Malignant Fibrous Histiocytoma
Mohs Surgery
Dermatofibrosarcoma
Neoplasms
Therapeutics
Recurrence

ASJC Scopus subject areas

  • Dermatology
  • Oncology

Cite this

Treatment of malignant fibrous histiocytoma and atypical fibrous xanthomas with micrographic surgery. / Brown, M. D.; Swanson, Neil.

In: Journal of Dermatologic Surgery and Oncology, Vol. 15, No. 12, 1989, p. 1287-1292.

Research output: Contribution to journalArticle

@article{5c3f2a0771d4473681036978b40802e8,
title = "Treatment of malignant fibrous histiocytoma and atypical fibrous xanthomas with micrographic surgery",
abstract = "Fibrous tumors of the soft tissue are usually benign, but some fibrous neoplasms such as dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrohistiocytoma (MFH) can be very destructive locally with a high recurrence rate after local excision. On occasion, they can metastasize. Previous reports have confirmed the high success rate of Mohs micrographic surgery for the treatment of DFSP, but data have been lacking on the potential benefit of this surgical approach for MFH and AFX tumors. Over the past 6 years, we have treated 17 patients with MFH (20 tumors) and 5 patients with AFX with Mohs micrographic surgery. A retrospective analysis of the surgical results is presented. To date (average 3-year follow-up), all patients contacted are tumor free with only one recurrence; no patient has developed metastatic disease. Our results to date are very encouraging; they lend support to Mohs micrographic surgery as a desired surgical approach for these difficult-to-cure neoplasms.",
author = "Brown, {M. D.} and Neil Swanson",
year = "1989",
language = "English (US)",
volume = "15",
pages = "1287--1292",
journal = "Dermatologic Surgery",
issn = "1076-0512",
publisher = "Wiley-Blackwell",
number = "12",

}

TY - JOUR

T1 - Treatment of malignant fibrous histiocytoma and atypical fibrous xanthomas with micrographic surgery

AU - Brown, M. D.

AU - Swanson, Neil

PY - 1989

Y1 - 1989

N2 - Fibrous tumors of the soft tissue are usually benign, but some fibrous neoplasms such as dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrohistiocytoma (MFH) can be very destructive locally with a high recurrence rate after local excision. On occasion, they can metastasize. Previous reports have confirmed the high success rate of Mohs micrographic surgery for the treatment of DFSP, but data have been lacking on the potential benefit of this surgical approach for MFH and AFX tumors. Over the past 6 years, we have treated 17 patients with MFH (20 tumors) and 5 patients with AFX with Mohs micrographic surgery. A retrospective analysis of the surgical results is presented. To date (average 3-year follow-up), all patients contacted are tumor free with only one recurrence; no patient has developed metastatic disease. Our results to date are very encouraging; they lend support to Mohs micrographic surgery as a desired surgical approach for these difficult-to-cure neoplasms.

AB - Fibrous tumors of the soft tissue are usually benign, but some fibrous neoplasms such as dermatofibrosarcoma protuberans (DFSP), atypical fibroxanthoma (AFX), and malignant fibrohistiocytoma (MFH) can be very destructive locally with a high recurrence rate after local excision. On occasion, they can metastasize. Previous reports have confirmed the high success rate of Mohs micrographic surgery for the treatment of DFSP, but data have been lacking on the potential benefit of this surgical approach for MFH and AFX tumors. Over the past 6 years, we have treated 17 patients with MFH (20 tumors) and 5 patients with AFX with Mohs micrographic surgery. A retrospective analysis of the surgical results is presented. To date (average 3-year follow-up), all patients contacted are tumor free with only one recurrence; no patient has developed metastatic disease. Our results to date are very encouraging; they lend support to Mohs micrographic surgery as a desired surgical approach for these difficult-to-cure neoplasms.

UR - http://www.scopus.com/inward/record.url?scp=0024804438&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024804438&partnerID=8YFLogxK

M3 - Article

C2 - 2556464

AN - SCOPUS:0024804438

VL - 15

SP - 1287

EP - 1292

JO - Dermatologic Surgery

JF - Dermatologic Surgery

SN - 1076-0512

IS - 12

ER -