Abstract
Background: Neurofibromatosis type 1 (NF1) is a multisystem disorder that causes multiple tumor formations throughout the nervous system. Common spinal dysplasias seen with NF1, such as dural ectasia (DE), often undergo modulation and predispose these patients to spondylolisthesis, making surgical treatment challenging. Case Description: A patient with NF1 presented with a 12-year-history of back and left lower extremity radicular pain. Lumbar spine magnetic resonance imaging revealed developmental anomalies with severe DE and associated scalloping of the L4-S1 vertebral bodies and severe L5-S1 Meyerding grade 4 spondylolisthesis. During surgery, post-positioning x-rays demonstrated a grade 5 spondyloptosis. The patient underwent an L5-S1 stand-alone anterior lumbar interbody fusion (ALIF). The final construct was an ALIF cage with one screw into S1, without an anterior plate. By 3-months post-operative, there was complete resolution of preoperative symptoms and at 2 year follow-up the patient was asymptomatic with stable hardware and solid bony fusion. To the authors’ knowledge, this is the first report of spondyloptosis treated with a stand-alone ALIF in a patient with NF1 and severe DE.
| Original language | English (US) |
|---|---|
| Journal | British Journal of Neurosurgery |
| DOIs |
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| State | Published - Jan 1 2019 |
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Keywords
- anterior lumbar interbody fusion
- dural ectasia
- Neurofibromatosis type 1
- spondylolisthesis
ASJC Scopus subject areas
- Surgery
- Clinical Neurology
Cite this
Treatment of L5-S1 spondyloptosis with stand-alone anterior lumbar interbody fusion in a patient with neurofibromatosis. / Cheaney, Barry; Krause, Katie L.; Jung, Enjae; Than, Khoi.
In: British Journal of Neurosurgery, 01.01.2019.Research output: Contribution to journal › Comment/debate
}
TY - JOUR
T1 - Treatment of L5-S1 spondyloptosis with stand-alone anterior lumbar interbody fusion in a patient with neurofibromatosis
AU - Cheaney, Barry
AU - Krause, Katie L.
AU - Jung, Enjae
AU - Than, Khoi
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Background: Neurofibromatosis type 1 (NF1) is a multisystem disorder that causes multiple tumor formations throughout the nervous system. Common spinal dysplasias seen with NF1, such as dural ectasia (DE), often undergo modulation and predispose these patients to spondylolisthesis, making surgical treatment challenging. Case Description: A patient with NF1 presented with a 12-year-history of back and left lower extremity radicular pain. Lumbar spine magnetic resonance imaging revealed developmental anomalies with severe DE and associated scalloping of the L4-S1 vertebral bodies and severe L5-S1 Meyerding grade 4 spondylolisthesis. During surgery, post-positioning x-rays demonstrated a grade 5 spondyloptosis. The patient underwent an L5-S1 stand-alone anterior lumbar interbody fusion (ALIF). The final construct was an ALIF cage with one screw into S1, without an anterior plate. By 3-months post-operative, there was complete resolution of preoperative symptoms and at 2 year follow-up the patient was asymptomatic with stable hardware and solid bony fusion. To the authors’ knowledge, this is the first report of spondyloptosis treated with a stand-alone ALIF in a patient with NF1 and severe DE.
AB - Background: Neurofibromatosis type 1 (NF1) is a multisystem disorder that causes multiple tumor formations throughout the nervous system. Common spinal dysplasias seen with NF1, such as dural ectasia (DE), often undergo modulation and predispose these patients to spondylolisthesis, making surgical treatment challenging. Case Description: A patient with NF1 presented with a 12-year-history of back and left lower extremity radicular pain. Lumbar spine magnetic resonance imaging revealed developmental anomalies with severe DE and associated scalloping of the L4-S1 vertebral bodies and severe L5-S1 Meyerding grade 4 spondylolisthesis. During surgery, post-positioning x-rays demonstrated a grade 5 spondyloptosis. The patient underwent an L5-S1 stand-alone anterior lumbar interbody fusion (ALIF). The final construct was an ALIF cage with one screw into S1, without an anterior plate. By 3-months post-operative, there was complete resolution of preoperative symptoms and at 2 year follow-up the patient was asymptomatic with stable hardware and solid bony fusion. To the authors’ knowledge, this is the first report of spondyloptosis treated with a stand-alone ALIF in a patient with NF1 and severe DE.
KW - anterior lumbar interbody fusion
KW - dural ectasia
KW - Neurofibromatosis type 1
KW - spondylolisthesis
UR - http://www.scopus.com/inward/record.url?scp=85062467812&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85062467812&partnerID=8YFLogxK
U2 - 10.1080/02688697.2019.1572868
DO - 10.1080/02688697.2019.1572868
M3 - Comment/debate
AN - SCOPUS:85062467812
JO - British Journal of Neurosurgery
JF - British Journal of Neurosurgery
SN - 0268-8697
ER -