Treatment of corticosteroid dependent optic neuropathy with intravenous immunoglobulin

Daryl Kurz, Robert A. Egan, James (Jim) Rosenbaum

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

PURPOSE: To report a patient with corticosteroid dependent optic neuropathy treated with intravenous immunoglobulin (IVIg). DESIGN: Interventional case report. METHODS: Records review. RESULTS: A 25-year-old woman developed bilateral vision loss with pain on eye movement in association with disk edema, dilated retinal veins, and hemorrhage. The vision improved markedly with prednisone, but she required a minimum of 20 mg/d despite concomitant therapy with methotrexate, cyclosporine, and/or mycophenolate mofetil. IVIg, 0.5 g/kg/d for 3 days each month with subsequent reduction in frequency, allowed discontinuation of all immunosuppression. CONCLUSIONS: Corticosteroid dependent optic neuropathy was successfully treated with IVIg.

Original languageEnglish (US)
Pages (from-to)1132-1133
Number of pages2
JournalAmerican Journal of Ophthalmology
Volume140
Issue number6
DOIs
StatePublished - Dec 2005

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Optic Nerve Diseases
Intravenous Immunoglobulins
Adrenal Cortex Hormones
Mycophenolic Acid
Retinal Hemorrhage
Retinal Vein
Eye Movements
Prednisone
Methotrexate
Immunosuppression
Cyclosporine
Edema
Therapeutics
Pain

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Treatment of corticosteroid dependent optic neuropathy with intravenous immunoglobulin. / Kurz, Daryl; Egan, Robert A.; Rosenbaum, James (Jim).

In: American Journal of Ophthalmology, Vol. 140, No. 6, 12.2005, p. 1132-1133.

Research output: Contribution to journalArticle

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