Treatment of a rapidly cycling bipolar patient by using extended bed rest and darkness to stabilize the timing and duration of sleep

Thomas A. Wehr, Erick Turner, Jeffrey M. Shimada, Catherine H. Lowe, Charles Barker, Ellen Leibenluft

Research output: Contribution to journalArticle

132 Citations (Scopus)

Abstract

Background: The modern practice of using artificial light to extend waking activities into the nighttime hours might be expected to precipitate or exacerbate bipolar illness, because it has been shown that modifying the timing and duration of sleep can induce mania in susceptible individuals. With this possibility in mind, we treated a patient with rapidly cycling bipolar illness by creating an environment that was likely to increase and to stabilize the number of hours that he slept each night. Methods: We asked the patient to remain at bed rest in the dark for 14 hours each night (later this was gradually reduced to 10 hours). Over a period of several years, his clinical state was assessed with twice-daily self-ratings, once-weekly observer ratings, and continuous wrist motor activity recordings. Times of sleeping and waking were recorded with sleep logs, polygraphic recordings, and computer-based event recordings. Results: The patient cycled rapidly between depression and mania and experienced marked fluctuations in the timing and duration of sleep when he slept according to his usual routine, but his sleep and mood stabilized when he adhered to a regimen of long nightly periods of enforced bed rest in the dark. Conclusions: Fostering sleep and stabilizing its timing by scheduling regular nightly periods of enforced bed rest in the dark may help to prevent mania and rapid cycling in bipolar patients.

Original languageEnglish (US)
Pages (from-to)822-828
Number of pages7
JournalBiological Psychiatry
Volume43
Issue number11
DOIs
StatePublished - Jun 1 1998
Externally publishedYes

Fingerprint

Bed Rest
Darkness
Sleep
Bipolar Disorder
Therapeutics
Foster Home Care
Wrist
Motor Activity
Depression
Light

Keywords

  • Circadian rhythm
  • Depression
  • Light
  • Mania
  • Motor activity
  • Photoperiod
  • Rapidly cycling bipolar disorder
  • Sleep
  • Sleep deprivation

ASJC Scopus subject areas

  • Biological Psychiatry

Cite this

Treatment of a rapidly cycling bipolar patient by using extended bed rest and darkness to stabilize the timing and duration of sleep. / Wehr, Thomas A.; Turner, Erick; Shimada, Jeffrey M.; Lowe, Catherine H.; Barker, Charles; Leibenluft, Ellen.

In: Biological Psychiatry, Vol. 43, No. 11, 01.06.1998, p. 822-828.

Research output: Contribution to journalArticle

Wehr, Thomas A. ; Turner, Erick ; Shimada, Jeffrey M. ; Lowe, Catherine H. ; Barker, Charles ; Leibenluft, Ellen. / Treatment of a rapidly cycling bipolar patient by using extended bed rest and darkness to stabilize the timing and duration of sleep. In: Biological Psychiatry. 1998 ; Vol. 43, No. 11. pp. 822-828.
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