Treatment of γ-aminobutyric acidB receptor-antibody autoimmune encephalitis with oral corticosteroids

Daniel M. Goldenholz, Victoria Wong, Lisa M. Bateman, Michelle Apperson, Bjorn Oskarsson, Shahrzad Akhtar, Vicki Wheelock

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Background : Autoimmune encephalitis is increasingly identified as a cause of nonviral, idiopathic encephalitis. Present treatment algorithms recommend costly immune-modulating treatments and do not identify a role for oral corticosteroids. Objective: To present a patient with γ-aminobutyric acidB receptor-antibody encephalitis before and after treatment with oral corticosteroids. Design : Case report. Setting: The inpatient course as well as outpatient fol-low- up is discussed. Patient: A 43-year-old man with initial presentation of seizures and altered mental status. Intervention : Our patient was treated with an extended course of oral corticosteroids as an outpatient. Results: After treatment with oral corticosteroids, our patient had steady clinical improvement, achieved seizure freedom, and experienced improved mental status to within normal limits. Conclusions: This case supports the use of low-cost oral corticosteroids in treating patients with γ-aminobutyric acidB receptor-antibody encephalitis.

Original languageEnglish (US)
Pages (from-to)1061-1063
Number of pages3
JournalArchives of Neurology
Volume69
Issue number8
DOIs
StatePublished - Aug 2012
Externally publishedYes

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Adrenal Cortex Hormones
Encephalitis
Antibodies
Seizures
Outpatients
Therapeutics
Inpatients
Hashimoto's encephalitis
Costs and Cost Analysis

ASJC Scopus subject areas

  • Clinical Neurology
  • Arts and Humanities (miscellaneous)

Cite this

Goldenholz, D. M., Wong, V., Bateman, L. M., Apperson, M., Oskarsson, B., Akhtar, S., & Wheelock, V. (2012). Treatment of γ-aminobutyric acidB receptor-antibody autoimmune encephalitis with oral corticosteroids. Archives of Neurology, 69(8), 1061-1063. https://doi.org/10.1001/archneurol.2012.197

Treatment of γ-aminobutyric acidB receptor-antibody autoimmune encephalitis with oral corticosteroids. / Goldenholz, Daniel M.; Wong, Victoria; Bateman, Lisa M.; Apperson, Michelle; Oskarsson, Bjorn; Akhtar, Shahrzad; Wheelock, Vicki.

In: Archives of Neurology, Vol. 69, No. 8, 08.2012, p. 1061-1063.

Research output: Contribution to journalArticle

Goldenholz, DM, Wong, V, Bateman, LM, Apperson, M, Oskarsson, B, Akhtar, S & Wheelock, V 2012, 'Treatment of γ-aminobutyric acidB receptor-antibody autoimmune encephalitis with oral corticosteroids', Archives of Neurology, vol. 69, no. 8, pp. 1061-1063. https://doi.org/10.1001/archneurol.2012.197
Goldenholz, Daniel M. ; Wong, Victoria ; Bateman, Lisa M. ; Apperson, Michelle ; Oskarsson, Bjorn ; Akhtar, Shahrzad ; Wheelock, Vicki. / Treatment of γ-aminobutyric acidB receptor-antibody autoimmune encephalitis with oral corticosteroids. In: Archives of Neurology. 2012 ; Vol. 69, No. 8. pp. 1061-1063.
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