Trajectories of the relationships of physical activity with body composition changes in older men: the MrOS study

Deepika R. Laddu, Peggy M. Cawthon, Neeta Parimi, Andrew R. Hoffman, Eric Orwoll, Iva Miljkovic, Marcia L. Stefanick

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Excess adiposity gains and significant lean mass loss may be risk factors for chronic disease in old age. Long-term patterns of change in physical activity (PA) and their influence on body composition decline during aging has not been characterized. We evaluated the interrelationships of PA and body composition at the outset and over longitudinal follow-up to changes in older men. Methods: Self-reported PA by the Physical Activity Scale for the Elderly (PASE), clinic body weight, and whole-body lean mass (LM) and fat mass, by dual-energy x-ray absorptiometry (DXA), were assessed in 5964 community-dwelling men aged ≥65 years at baseline (2000-2002) and at two subsequent clinic visits up until March 2009 (an average 4.6 and 6.9 years later). Group-based trajectory modeling (GBTM) identified patterns of change in PA and body composition variables. Relationships of PA and body composition changes were then assessed. Results: GBTM identified three discrete trajectory patterns, all with declining PA, associated primarily with initial PA levelshigh-activity (7.2% of men), moderate-activity (50.0%), and low-activity (42.8%). In separate models, GBTM identified eight discrete total weight change groups, five fat mass change groups, and six LM change groups. Joint trajectory modeling by PA and body composition group illustrated significant declines in total weight and LM, whereas fat mass levels were relatively unchanged among high-activity and low-activity-declining groups, and significantly increased in the moderate-activity-declining group. Conclusion: Although patterns of change in PA and body composition were identified, groups were primarily differentiated by initial PA or body composition rather than by distinct trajectories of change in these variables.

Original languageEnglish (US)
Article number119
JournalBMC Geriatrics
Volume17
Issue number1
DOIs
StatePublished - Jun 5 2017

Fingerprint

Body Composition
Exercise
Fats
Independent Living
Weights and Measures
Adiposity
Ambulatory Care
Chronic Disease
Joints
Body Weight
X-Rays

Keywords

  • Fat mass
  • Lean mass
  • Older men
  • Physical activity
  • Trajectories

ASJC Scopus subject areas

  • Geriatrics and Gerontology

Cite this

Trajectories of the relationships of physical activity with body composition changes in older men : the MrOS study. / Laddu, Deepika R.; Cawthon, Peggy M.; Parimi, Neeta; Hoffman, Andrew R.; Orwoll, Eric; Miljkovic, Iva; Stefanick, Marcia L.

In: BMC Geriatrics, Vol. 17, No. 1, 119, 05.06.2017.

Research output: Contribution to journalArticle

Laddu, Deepika R. ; Cawthon, Peggy M. ; Parimi, Neeta ; Hoffman, Andrew R. ; Orwoll, Eric ; Miljkovic, Iva ; Stefanick, Marcia L. / Trajectories of the relationships of physical activity with body composition changes in older men : the MrOS study. In: BMC Geriatrics. 2017 ; Vol. 17, No. 1.
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abstract = "Background: Excess adiposity gains and significant lean mass loss may be risk factors for chronic disease in old age. Long-term patterns of change in physical activity (PA) and their influence on body composition decline during aging has not been characterized. We evaluated the interrelationships of PA and body composition at the outset and over longitudinal follow-up to changes in older men. Methods: Self-reported PA by the Physical Activity Scale for the Elderly (PASE), clinic body weight, and whole-body lean mass (LM) and fat mass, by dual-energy x-ray absorptiometry (DXA), were assessed in 5964 community-dwelling men aged ≥65 years at baseline (2000-2002) and at two subsequent clinic visits up until March 2009 (an average 4.6 and 6.9 years later). Group-based trajectory modeling (GBTM) identified patterns of change in PA and body composition variables. Relationships of PA and body composition changes were then assessed. Results: GBTM identified three discrete trajectory patterns, all with declining PA, associated primarily with initial PA levelshigh-activity (7.2{\%} of men), moderate-activity (50.0{\%}), and low-activity (42.8{\%}). In separate models, GBTM identified eight discrete total weight change groups, five fat mass change groups, and six LM change groups. Joint trajectory modeling by PA and body composition group illustrated significant declines in total weight and LM, whereas fat mass levels were relatively unchanged among high-activity and low-activity-declining groups, and significantly increased in the moderate-activity-declining group. Conclusion: Although patterns of change in PA and body composition were identified, groups were primarily differentiated by initial PA or body composition rather than by distinct trajectories of change in these variables.",
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AU - Laddu, Deepika R.

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AU - Orwoll, Eric

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AB - Background: Excess adiposity gains and significant lean mass loss may be risk factors for chronic disease in old age. Long-term patterns of change in physical activity (PA) and their influence on body composition decline during aging has not been characterized. We evaluated the interrelationships of PA and body composition at the outset and over longitudinal follow-up to changes in older men. Methods: Self-reported PA by the Physical Activity Scale for the Elderly (PASE), clinic body weight, and whole-body lean mass (LM) and fat mass, by dual-energy x-ray absorptiometry (DXA), were assessed in 5964 community-dwelling men aged ≥65 years at baseline (2000-2002) and at two subsequent clinic visits up until March 2009 (an average 4.6 and 6.9 years later). Group-based trajectory modeling (GBTM) identified patterns of change in PA and body composition variables. Relationships of PA and body composition changes were then assessed. Results: GBTM identified three discrete trajectory patterns, all with declining PA, associated primarily with initial PA levelshigh-activity (7.2% of men), moderate-activity (50.0%), and low-activity (42.8%). In separate models, GBTM identified eight discrete total weight change groups, five fat mass change groups, and six LM change groups. Joint trajectory modeling by PA and body composition group illustrated significant declines in total weight and LM, whereas fat mass levels were relatively unchanged among high-activity and low-activity-declining groups, and significantly increased in the moderate-activity-declining group. Conclusion: Although patterns of change in PA and body composition were identified, groups were primarily differentiated by initial PA or body composition rather than by distinct trajectories of change in these variables.

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