Total pancreatectomy with islet autotransplantation summary of a national institute of diabetes and digestive and kidney diseases workshop

Melena D. Bellin, Andres Gelrud, Guillermo Arreaza-Rubin, Ty B. Dunn, Abhinav Humar, Katherine A. Morgan, Bashoo Naziruddin, Cristiana Rastellini, Michael R. Rickels, Sarah J. Schwarzenberg, Dana Andersen

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

A workshop sponsored by the National Institute of Diabetes and Digestive and Kidney Diseases focused on research gaps and opportunities in total pancreatectomy with islet autotransplantation (TPIAT) for the management of chronic pancreatitis (CP). The session was held on July 23, 2014, and structured into 5 sessions: (1) patient selection, indications, and timing; (2) technical aspects of TPIAT; (3) improving success of islet autotransplantation; (4) improving outcomes after total pancreatectomy; and (5) registry considerations for TPIAT. The current state of knowledge was reviewed; knowledge gaps and research needs were specifically highlighted. Common themes included the need to identify which patients best benefit from and when to intervene with TPIAT, current limitations of the surgical procedure, diabetes remission and the potential for improvement, opportunities to better address pain remission, gastrointestinal complications in this population, and unique features of children with CP considered for TPIAT. The need for a multicenter patient registry that specifically addresses the complexities of CP and total pancreatectomy outcomes as well as postsurgical diabetes outcomes was repeatedly emphasized.

Original languageEnglish (US)
Pages (from-to)1163-1170
Number of pages8
JournalPancreas
Volume43
Issue number8
StatePublished - Nov 10 2014
Externally publishedYes

Fingerprint

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Pancreatectomy
Autologous Transplantation
Education
Chronic Pancreatitis
Registries
Research
Patient Selection
Pain

Keywords

  • Chronic pancreatitis
  • Diabetes
  • Islet transplantation
  • Pain
  • Pancreatectomy
  • Pancreatic exocrine insufficiency

ASJC Scopus subject areas

  • Hepatology
  • Internal Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Bellin, M. D., Gelrud, A., Arreaza-Rubin, G., Dunn, T. B., Humar, A., Morgan, K. A., ... Andersen, D. (2014). Total pancreatectomy with islet autotransplantation summary of a national institute of diabetes and digestive and kidney diseases workshop. Pancreas, 43(8), 1163-1170.

Total pancreatectomy with islet autotransplantation summary of a national institute of diabetes and digestive and kidney diseases workshop. / Bellin, Melena D.; Gelrud, Andres; Arreaza-Rubin, Guillermo; Dunn, Ty B.; Humar, Abhinav; Morgan, Katherine A.; Naziruddin, Bashoo; Rastellini, Cristiana; Rickels, Michael R.; Schwarzenberg, Sarah J.; Andersen, Dana.

In: Pancreas, Vol. 43, No. 8, 10.11.2014, p. 1163-1170.

Research output: Contribution to journalArticle

Bellin, MD, Gelrud, A, Arreaza-Rubin, G, Dunn, TB, Humar, A, Morgan, KA, Naziruddin, B, Rastellini, C, Rickels, MR, Schwarzenberg, SJ & Andersen, D 2014, 'Total pancreatectomy with islet autotransplantation summary of a national institute of diabetes and digestive and kidney diseases workshop', Pancreas, vol. 43, no. 8, pp. 1163-1170.
Bellin MD, Gelrud A, Arreaza-Rubin G, Dunn TB, Humar A, Morgan KA et al. Total pancreatectomy with islet autotransplantation summary of a national institute of diabetes and digestive and kidney diseases workshop. Pancreas. 2014 Nov 10;43(8):1163-1170.
Bellin, Melena D. ; Gelrud, Andres ; Arreaza-Rubin, Guillermo ; Dunn, Ty B. ; Humar, Abhinav ; Morgan, Katherine A. ; Naziruddin, Bashoo ; Rastellini, Cristiana ; Rickels, Michael R. ; Schwarzenberg, Sarah J. ; Andersen, Dana. / Total pancreatectomy with islet autotransplantation summary of a national institute of diabetes and digestive and kidney diseases workshop. In: Pancreas. 2014 ; Vol. 43, No. 8. pp. 1163-1170.
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