Total anomalous pulmonary venous connection in neonates and young infants: Repair in the current era

Adnan Cobanoglu, Victor Menashe

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Total anomalous pulmonary venous connection has been one of the more challenging congenital heart defects in newborns and young infants despite improvements in surgical technique, cardiac anesthesia, neonatal myocardial preservation, and postoperative care. Since 1981, 30 patients with total anomalous pulmonary venous connection have undergone primary total correction. Mean age at operation was 28 ± 6 days and mean weight, 3.3 ± 0.7 kg. Essential features of the surgical approach in these small patients included early surgical intervention, profound hypothermia with total circulatory arrest, cardioplegic myocardial preservation, and a wide posterior anastomosis. Operative mortality was 13% ± 6%. All four deaths were in patients having emergency operation within 24 hours of the surgical consult and requiring ventilator support preoperatively. The mean follow-up is 47 ± 7 months. There have been two late deaths, and the 7-year survival rate is 79% ± 8%. There have been two reoperations, and 91% ± 6% of the patients are reoperation free at 7 years. Only 1 of the 24 surviving patients is symptomatic. Growth in survivors is closely monitored. The height growth percentile is less than 5% in 15% ± 8% of survivors and the weight growth percentile, less than 5% in 17 ± 8%. During the past decade, with a consistent surgical approach to neonates and infants with total anomalous pulmonary venous connection, it has been possible to achieve low early mortality, low attrition, and excellent late results.

Original languageEnglish (US)
Pages (from-to)43-49
Number of pages7
JournalThe Annals of Thoracic Surgery
Volume55
Issue number1
DOIs
StatePublished - 1993

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Newborn Infant
Lung
Reoperation
Survivors
Growth
Weights and Measures
Congenital Heart Defects
Mortality
Postoperative Care
Mechanical Ventilators
Hypothermia
Emergencies
Survival Rate
Anesthesia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Total anomalous pulmonary venous connection in neonates and young infants : Repair in the current era. / Cobanoglu, Adnan; Menashe, Victor.

In: The Annals of Thoracic Surgery, Vol. 55, No. 1, 1993, p. 43-49.

Research output: Contribution to journalArticle

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