Top Questions in the Diagnosis and Treatment of Pulmonary M. abscessus Disease

Ruvandhi R. Nathavitharana, Luke Strnad, Philip A. Lederer, Maunank Shah, Rocio M. Hurtado

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Mycobacterium abscessus disease is particularly challenging to treat, given the intrinsic drug resistance of this species and the limited data on which recommendations are based, resulting in a greater reliance on expert opinion. We address several commonly encountered questions and management considerations regarding pulmonary Mycobacterium abscessus disease, including the role of subspecies identification, diagnostic criteria for determining disease, interpretation of drug susceptibility test results, approach to therapy including the need for parenteral antibiotics and the role for new and repurposed drugs, and the use of adjunctive strategies such as airway clearance and surgical resection.

Original languageEnglish (US)
Article numberofz221
JournalOpen Forum Infectious Diseases
Volume6
Issue number7
DOIs
StatePublished - Jul 1 2019

Keywords

  • bronchiectasis
  • drug resistance
  • lung disease
  • mycobacterium abscessus
  • non-tuberculous mycobacteria

ASJC Scopus subject areas

  • Oncology
  • Clinical Neurology

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