TY - JOUR
T1 - Tools for exploring mouse models of human disease
AU - Haendel, Melissa
AU - Papatheodorou, Irene
AU - Oellrich, Anika
AU - Mungall, Christopher J.
AU - Washington, Nicole
AU - Lewis, Suzanna E.
AU - Robinson, Peter N.
AU - Smedley, Damian
PY - 2016/2/2
Y1 - 2016/2/2
N2 - Despite significant computational challenges, a number of tools have been developed recently to leverage the mouse to model human disease. Here we review these tools and show how they can be applied in the identification of candidate genes and therapeutic targets as well as mouse models for mechanistic studies and drug validation.
AB - Despite significant computational challenges, a number of tools have been developed recently to leverage the mouse to model human disease. Here we review these tools and show how they can be applied in the identification of candidate genes and therapeutic targets as well as mouse models for mechanistic studies and drug validation.
UR - http://www.scopus.com/inward/record.url?scp=85028363418&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85028363418&partnerID=8YFLogxK
U2 - 10.1016/j.ddmod.2017.07.004
DO - 10.1016/j.ddmod.2017.07.004
M3 - Review article
AN - SCOPUS:85028363418
VL - 20
SP - 21
EP - 26
JO - Drug Discovery Today: Disease Models
JF - Drug Discovery Today: Disease Models
SN - 1740-6757
ER -