Tobacco use among adults initiating treatment for HIV infection in rural uganda

Gina R. Kruse; David R. Bangsberg; Judith A. Hahn; Jessica E. Haberer; Peter W. Hunt; Conrad Muzoora; John P. Bennett; Jeffrey N. Martin; Nancy A. Rigotti

doi:10.1007/s10461-014-0737-8

Tobacco use among adults initiating treatment for HIV infection in rural uganda

Gina R. Kruse, David R. Bangsberg, Judith A. Hahn, Jessica E. Haberer, Peter W. Hunt, Conrad Muzoora, John P. Bennett, Jeffrey N. Martin, Nancy A. Rigotti

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

We conducted a longitudinal study of tobacco use among adults initiating antiretroviral therapy (ART) in Mbarara, Uganda where 11 % of men and 3 % of women use tobacco according to the 2011 Demographic and Health Survey. In a prospective cohort, self-reported tobacco use was assessed before starting ART and reassessed every 3-4 months. Plasma cotinine, a nicotine metabolite, was measured in a subset of adults pre-ART to verify self-report. Among 496 subjects, 50 (10 %) reported current tobacco use (20 % of men, 6 % of women). Most (53 %) adults with elevated cotinine levels (>15 ng/mL) reported no tobacco use. By 6 months after ART initiation, 33 % of tobacco users had quit (95 % CI 20-46 %). By 5 years, 64 % quit (95 % CI 47-77 %). Self-reported tobacco use among rural Ugandans starting ART was twice as common as among the local background population and use may be underreported. ART initiation could be an opportunity for tobacco cessation interventions.

Original language	English (US)
Pages (from-to)	1381-1389
Number of pages	9
Journal	AIDS and Behavior
Volume	18
Issue number	7
DOIs	https://doi.org/10.1007/s10461-014-0737-8
State	Published - Jul 2014
Externally published	Yes

Keywords

Antiretroviral treatment initiation
Resource-limited setting
Smoking cessation
Socioeconomic status
Tobacco use

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1007/s10461-014-0737-8

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@article{1d9a12517fab4e35b344a39d8ebb12d3,

title = "Tobacco use among adults initiating treatment for HIV infection in rural uganda",

abstract = "We conducted a longitudinal study of tobacco use among adults initiating antiretroviral therapy (ART) in Mbarara, Uganda where 11 % of men and 3 % of women use tobacco according to the 2011 Demographic and Health Survey. In a prospective cohort, self-reported tobacco use was assessed before starting ART and reassessed every 3-4 months. Plasma cotinine, a nicotine metabolite, was measured in a subset of adults pre-ART to verify self-report. Among 496 subjects, 50 (10 %) reported current tobacco use (20 % of men, 6 % of women). Most (53 %) adults with elevated cotinine levels (>15 ng/mL) reported no tobacco use. By 6 months after ART initiation, 33 % of tobacco users had quit (95 % CI 20-46 %). By 5 years, 64 % quit (95 % CI 47-77 %). Self-reported tobacco use among rural Ugandans starting ART was twice as common as among the local background population and use may be underreported. ART initiation could be an opportunity for tobacco cessation interventions.",

keywords = "Antiretroviral treatment initiation, Resource-limited setting, Smoking cessation, Socioeconomic status, Tobacco use",

author = "Kruse, {Gina R.} and Bangsberg, {David R.} and Hahn, {Judith A.} and Haberer, {Jessica E.} and Hunt, {Peter W.} and Conrad Muzoora and Bennett, {John P.} and Martin, {Jeffrey N.} and Rigotti, {Nancy A.}",

note = "Funding Information: Acknowledgments We would like to acknowledge the contributions of Dr. Martin A. Javors. Dr. Javors conducted the cotinine assays for the subset that was tested and provided helpful feedback on the reporting of the cotinine results. The Ugandan AIDS Rural Treatment Outcomes study was funded by U.S. National Institutes of Health (NIH) R01 MH-054907, K23 MH-079713, K23 MH-079713-03S1, and P30 AI-027763. Dr. Kruse was supported by Grant T32HP12706-03-00 from the Health Resources and Services Administration for the Harvard General Medicine Fellowship and the Ryoichi Sasakawa Fellowship Fund. Dr. Bangsberg was funded by NIH Grant K24 MH87227. Dr. Haberer was funded by NIH Grant K23 087228. The funders of these grants had no role in study design, conduct, data analysis, interpretation, or manuscript preparation, review, or approval. An earlier version of this work was presented as a poster at the Society for Research on Nicotine and Tobacco 19th Annual meeting on March 16, 2013 in Boston, MA",

year = "2014",

month = jul,

doi = "10.1007/s10461-014-0737-8",

language = "English (US)",

volume = "18",

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T1 - Tobacco use among adults initiating treatment for HIV infection in rural uganda

AU - Kruse, Gina R.

AU - Bangsberg, David R.

AU - Hahn, Judith A.

AU - Haberer, Jessica E.

AU - Hunt, Peter W.

AU - Muzoora, Conrad

AU - Bennett, John P.

AU - Martin, Jeffrey N.

AU - Rigotti, Nancy A.

N1 - Funding Information: Acknowledgments We would like to acknowledge the contributions of Dr. Martin A. Javors. Dr. Javors conducted the cotinine assays for the subset that was tested and provided helpful feedback on the reporting of the cotinine results. The Ugandan AIDS Rural Treatment Outcomes study was funded by U.S. National Institutes of Health (NIH) R01 MH-054907, K23 MH-079713, K23 MH-079713-03S1, and P30 AI-027763. Dr. Kruse was supported by Grant T32HP12706-03-00 from the Health Resources and Services Administration for the Harvard General Medicine Fellowship and the Ryoichi Sasakawa Fellowship Fund. Dr. Bangsberg was funded by NIH Grant K24 MH87227. Dr. Haberer was funded by NIH Grant K23 087228. The funders of these grants had no role in study design, conduct, data analysis, interpretation, or manuscript preparation, review, or approval. An earlier version of this work was presented as a poster at the Society for Research on Nicotine and Tobacco 19th Annual meeting on March 16, 2013 in Boston, MA

PY - 2014/7

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N2 - We conducted a longitudinal study of tobacco use among adults initiating antiretroviral therapy (ART) in Mbarara, Uganda where 11 % of men and 3 % of women use tobacco according to the 2011 Demographic and Health Survey. In a prospective cohort, self-reported tobacco use was assessed before starting ART and reassessed every 3-4 months. Plasma cotinine, a nicotine metabolite, was measured in a subset of adults pre-ART to verify self-report. Among 496 subjects, 50 (10 %) reported current tobacco use (20 % of men, 6 % of women). Most (53 %) adults with elevated cotinine levels (>15 ng/mL) reported no tobacco use. By 6 months after ART initiation, 33 % of tobacco users had quit (95 % CI 20-46 %). By 5 years, 64 % quit (95 % CI 47-77 %). Self-reported tobacco use among rural Ugandans starting ART was twice as common as among the local background population and use may be underreported. ART initiation could be an opportunity for tobacco cessation interventions.

AB - We conducted a longitudinal study of tobacco use among adults initiating antiretroviral therapy (ART) in Mbarara, Uganda where 11 % of men and 3 % of women use tobacco according to the 2011 Demographic and Health Survey. In a prospective cohort, self-reported tobacco use was assessed before starting ART and reassessed every 3-4 months. Plasma cotinine, a nicotine metabolite, was measured in a subset of adults pre-ART to verify self-report. Among 496 subjects, 50 (10 %) reported current tobacco use (20 % of men, 6 % of women). Most (53 %) adults with elevated cotinine levels (>15 ng/mL) reported no tobacco use. By 6 months after ART initiation, 33 % of tobacco users had quit (95 % CI 20-46 %). By 5 years, 64 % quit (95 % CI 47-77 %). Self-reported tobacco use among rural Ugandans starting ART was twice as common as among the local background population and use may be underreported. ART initiation could be an opportunity for tobacco cessation interventions.

KW - Antiretroviral treatment initiation

KW - Resource-limited setting

KW - Smoking cessation

KW - Socioeconomic status

KW - Tobacco use

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Tobacco use among adults initiating treatment for HIV infection in rural uganda

Abstract

Keywords

ASJC Scopus subject areas

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