Timing of pulmonary emboli after trauma: Implications for retrievable vena cava filters

Ronald F. Sing, Steven M. Camp, B. Todd Heniford, Edmund J. Rutherford, Stephanie Dix, Patrick M. Reilly, James H. Holmes, Elliott Haut, Awori Hayanga, Frederick B. Rogers, William S. Hoff, Richard Mullins, H. David Root

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Background: Four recent reports of the retrieval of optional vena cava filters (VCF) in trauma patients had average implant durations of 10, 19, and 19 days (one not specified). Two patients in these studies had pulmonary emboli after VCF removal. No evidence-based guidelines exist on the appropriate time to remove optional VCF. The purpose of this study was to examine the timing of pulmonary emboli (PE) and determine the optimal time to remove optional VCFs. Methods: A multicenter retrospective chart review of trauma patients who had a postinjury PE between January 2001 and December 2004 was performed. We examined the demographics, prophylaxis at the time of PE (pharmacologic [unfractionated or low molecular weight heparin] or sequential compression devices [SCD]), diagnostic test used, timing of PE from the date of injury, and survival outcome. Results: In all, 146 patients were identified, mean age 45.1 (± 21.1 SD); Injury Severity Score 18.0 (± 12.1 SD). Diagnosis was obtained by spiral computed tomography (N = 93), pulmonary arteriogram (N = 18), V/Q (N = 26), autopsy (N = 6), clinical (N = 6), and unknown (N = 3). Overall mortality was 17.8% (N = 26). Pulmonary embolism was felt to contribute to or was the cause of death in 85% (N = 22) of these patients. Two late PE deaths occurred (days 21 and 43). Sixty (37%) patients had pharmacologic prophylaxis at the time of PE and 83 (50.9%) had SCDs. Average tune from injury to PE was 7.9 days (± 8.1 SD), the longest being 43 days postinjury. Eleven percent of PE occurred after 21 days, including fatal PE. Conclusions: Clinical criteria defining the time to remove optional VCFs without exposing patients to the risk of PE by removing a filter too soon should be determined.

Original languageEnglish (US)
Pages (from-to)732-735
Number of pages4
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume60
Issue number4
DOIs
StatePublished - Apr 2006
Externally publishedYes

Fingerprint

Vena Cava Filters
Embolism
Lung
Wounds and Injuries
Injury Severity Score
Spiral Computed Tomography
Low Molecular Weight Heparin
Lung Injury
Pulmonary Embolism
Routine Diagnostic Tests
Cause of Death
Autopsy

Keywords

  • Pulmonary embolism
  • Thromboembelism
  • Vena cava filter

ASJC Scopus subject areas

  • Surgery

Cite this

Sing, R. F., Camp, S. M., Heniford, B. T., Rutherford, E. J., Dix, S., Reilly, P. M., ... Root, H. D. (2006). Timing of pulmonary emboli after trauma: Implications for retrievable vena cava filters. Journal of Trauma - Injury, Infection and Critical Care, 60(4), 732-735. https://doi.org/10.1097/01.ta.0000210285.22571.66

Timing of pulmonary emboli after trauma : Implications for retrievable vena cava filters. / Sing, Ronald F.; Camp, Steven M.; Heniford, B. Todd; Rutherford, Edmund J.; Dix, Stephanie; Reilly, Patrick M.; Holmes, James H.; Haut, Elliott; Hayanga, Awori; Rogers, Frederick B.; Hoff, William S.; Mullins, Richard; Root, H. David.

In: Journal of Trauma - Injury, Infection and Critical Care, Vol. 60, No. 4, 04.2006, p. 732-735.

Research output: Contribution to journalArticle

Sing, RF, Camp, SM, Heniford, BT, Rutherford, EJ, Dix, S, Reilly, PM, Holmes, JH, Haut, E, Hayanga, A, Rogers, FB, Hoff, WS, Mullins, R & Root, HD 2006, 'Timing of pulmonary emboli after trauma: Implications for retrievable vena cava filters', Journal of Trauma - Injury, Infection and Critical Care, vol. 60, no. 4, pp. 732-735. https://doi.org/10.1097/01.ta.0000210285.22571.66
Sing, Ronald F. ; Camp, Steven M. ; Heniford, B. Todd ; Rutherford, Edmund J. ; Dix, Stephanie ; Reilly, Patrick M. ; Holmes, James H. ; Haut, Elliott ; Hayanga, Awori ; Rogers, Frederick B. ; Hoff, William S. ; Mullins, Richard ; Root, H. David. / Timing of pulmonary emboli after trauma : Implications for retrievable vena cava filters. In: Journal of Trauma - Injury, Infection and Critical Care. 2006 ; Vol. 60, No. 4. pp. 732-735.
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abstract = "Background: Four recent reports of the retrieval of optional vena cava filters (VCF) in trauma patients had average implant durations of 10, 19, and 19 days (one not specified). Two patients in these studies had pulmonary emboli after VCF removal. No evidence-based guidelines exist on the appropriate time to remove optional VCF. The purpose of this study was to examine the timing of pulmonary emboli (PE) and determine the optimal time to remove optional VCFs. Methods: A multicenter retrospective chart review of trauma patients who had a postinjury PE between January 2001 and December 2004 was performed. We examined the demographics, prophylaxis at the time of PE (pharmacologic [unfractionated or low molecular weight heparin] or sequential compression devices [SCD]), diagnostic test used, timing of PE from the date of injury, and survival outcome. Results: In all, 146 patients were identified, mean age 45.1 (± 21.1 SD); Injury Severity Score 18.0 (± 12.1 SD). Diagnosis was obtained by spiral computed tomography (N = 93), pulmonary arteriogram (N = 18), V/Q (N = 26), autopsy (N = 6), clinical (N = 6), and unknown (N = 3). Overall mortality was 17.8{\%} (N = 26). Pulmonary embolism was felt to contribute to or was the cause of death in 85{\%} (N = 22) of these patients. Two late PE deaths occurred (days 21 and 43). Sixty (37{\%}) patients had pharmacologic prophylaxis at the time of PE and 83 (50.9{\%}) had SCDs. Average tune from injury to PE was 7.9 days (± 8.1 SD), the longest being 43 days postinjury. Eleven percent of PE occurred after 21 days, including fatal PE. Conclusions: Clinical criteria defining the time to remove optional VCFs without exposing patients to the risk of PE by removing a filter too soon should be determined.",
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T2 - Implications for retrievable vena cava filters

AU - Sing, Ronald F.

AU - Camp, Steven M.

AU - Heniford, B. Todd

AU - Rutherford, Edmund J.

AU - Dix, Stephanie

AU - Reilly, Patrick M.

AU - Holmes, James H.

AU - Haut, Elliott

AU - Hayanga, Awori

AU - Rogers, Frederick B.

AU - Hoff, William S.

AU - Mullins, Richard

AU - Root, H. David

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N2 - Background: Four recent reports of the retrieval of optional vena cava filters (VCF) in trauma patients had average implant durations of 10, 19, and 19 days (one not specified). Two patients in these studies had pulmonary emboli after VCF removal. No evidence-based guidelines exist on the appropriate time to remove optional VCF. The purpose of this study was to examine the timing of pulmonary emboli (PE) and determine the optimal time to remove optional VCFs. Methods: A multicenter retrospective chart review of trauma patients who had a postinjury PE between January 2001 and December 2004 was performed. We examined the demographics, prophylaxis at the time of PE (pharmacologic [unfractionated or low molecular weight heparin] or sequential compression devices [SCD]), diagnostic test used, timing of PE from the date of injury, and survival outcome. Results: In all, 146 patients were identified, mean age 45.1 (± 21.1 SD); Injury Severity Score 18.0 (± 12.1 SD). Diagnosis was obtained by spiral computed tomography (N = 93), pulmonary arteriogram (N = 18), V/Q (N = 26), autopsy (N = 6), clinical (N = 6), and unknown (N = 3). Overall mortality was 17.8% (N = 26). Pulmonary embolism was felt to contribute to or was the cause of death in 85% (N = 22) of these patients. Two late PE deaths occurred (days 21 and 43). Sixty (37%) patients had pharmacologic prophylaxis at the time of PE and 83 (50.9%) had SCDs. Average tune from injury to PE was 7.9 days (± 8.1 SD), the longest being 43 days postinjury. Eleven percent of PE occurred after 21 days, including fatal PE. Conclusions: Clinical criteria defining the time to remove optional VCFs without exposing patients to the risk of PE by removing a filter too soon should be determined.

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KW - Thromboembelism

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