Time resolved propagation of ultrashort laser pulses within turbid tissues

Steven Jacques

Research output: Contribution to journalArticle

131 Scopus citations

Abstract

The time resolved propagation of femtosecond and picosecond laser pulses within turbid tissues is simulated by a Monte Carlo model. The internal distribution of irradiance for an impulse vs a 4-ps pulse is specified at different times for various scattering coefficients and scattering phase functions. Such simulations provide time resolved dosimetry for predicting the distribution of single- and two-photon chemical reactions in turbid tissues. For femtosecond pulses in highly scattering tissues, two-photon reactions are dominated by the initial primary (unscattered, unabsorbed) pulse, and single-photon reactions are dominated by the scattered diffuse irradiance. For picosecond pulses in highly scattering tissues, both single- and two-photon reactions are dominated by the scattered irradiance.

Original languageEnglish (US)
Pages (from-to)2223-2229
Number of pages7
JournalApplied Optics
Volume28
Issue number12
DOIs
StatePublished - Jun 15 1989
Externally publishedYes

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

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