Abstract
We investigate the relationship between the apparent absorption coefficient and actual absorption coefficient inside the vessels. This analytical formula predicts that the apparent absorption coefficient measured on a biological organ is a volume-weighted sum of the absorption coefficients of different absorbing components. Further, we present some apparent absorption coefficients measured in vivo in animals and humans and show that ignoring the background absorption can lead to significant errors in oxygenation determination.
| Original language | English (US) |
|---|---|
| Title of host publication | Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media |
| Subtitle of host publication | Theory, Human Studies, and Instrumentation |
| Editors | Britton Chance, Robert R. Alfano |
| Publisher | SPIE |
| Pages | 150-156 |
| Number of pages | 7 |
| Volume | 2389 |
| ISBN (Electronic) | 9780819417367 |
| DOIs | |
| State | Published - May 30 1995 |
| Externally published | Yes |
| Event | Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation - San Jose, United States Duration: Feb 1 1995 → Feb 28 1995 |
Other
| Other | Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation |
|---|---|
| Country | United States |
| City | San Jose |
| Period | 2/1/95 → 2/28/95 |
Fingerprint
Keywords
- blood oxygenation
- blood vessels
- hemoglobin absorption
- Heterogeneity
- Me-resolved reflectance
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering
Cite this
Time-resolved photon migration in a heterogeneous tissue-vessel model. / Liu, Hanli; Hielscher, Andreas H.; Kurth, Dean C.; Jacques, Steven; Chance, Britton.
Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation. ed. / Britton Chance; Robert R. Alfano. Vol. 2389 SPIE, 1995. p. 150-156.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Time-resolved photon migration in a heterogeneous tissue-vessel model
AU - Liu, Hanli
AU - Hielscher, Andreas H.
AU - Kurth, Dean C.
AU - Jacques, Steven
AU - Chance, Britton
PY - 1995/5/30
Y1 - 1995/5/30
N2 - We investigate the relationship between the apparent absorption coefficient and actual absorption coefficient inside the vessels. This analytical formula predicts that the apparent absorption coefficient measured on a biological organ is a volume-weighted sum of the absorption coefficients of different absorbing components. Further, we present some apparent absorption coefficients measured in vivo in animals and humans and show that ignoring the background absorption can lead to significant errors in oxygenation determination.
AB - We investigate the relationship between the apparent absorption coefficient and actual absorption coefficient inside the vessels. This analytical formula predicts that the apparent absorption coefficient measured on a biological organ is a volume-weighted sum of the absorption coefficients of different absorbing components. Further, we present some apparent absorption coefficients measured in vivo in animals and humans and show that ignoring the background absorption can lead to significant errors in oxygenation determination.
KW - blood oxygenation
KW - blood vessels
KW - hemoglobin absorption
KW - Heterogeneity
KW - Me-resolved reflectance
UR - http://www.scopus.com/inward/record.url?scp=84968066287&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84968066287&partnerID=8YFLogxK
U2 - 10.1117/12.209961
DO - 10.1117/12.209961
M3 - Conference contribution
AN - SCOPUS:84968066287
VL - 2389
SP - 150
EP - 156
BT - Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media
A2 - Chance, Britton
A2 - Alfano, Robert R.
PB - SPIE
ER -