Time resolved diffuse reflectance and transmittance studies in tissue simulating phantoms. A comparison between theory and experiment

Steen J. Madsen, Michael S. Patterson, Brian C. Wilson, Young D. Park, J. David Moulton, Steven L. Jacques, Yaron Hefetz

Research output: Contribution to journalConference articlepeer-review

16 Scopus citations

Abstract

When a picosecond light pulse is incident on an optically turbid medium such as tissue, the temporal distribution of diffusely reflected and transmitted photons depends on the optical absorption and scattering properties of the medium. From diffusion theory it is possible to derive analytical expressions for the pulse shape in terms of the optical interaction coefficients of a homogeneous semi-infinite medium. Experimental tests of this model in tissue-simulating liquid phantoms of different geometries are presented here.

Original languageEnglish (US)
Pages (from-to)42-51
Number of pages10
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume1431
StatePublished - Jan 1 1991
Externally publishedYes
EventProceedings of Time-Resolved Spectroscopy and Imaging of Tissues - Los Angeles, CA, USA
Duration: Jan 23 1991Jan 24 1991

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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