Time-dependent inhibition of oxotremorine-induced cerebral hyperemia by n sup omega-nitro-l-arginine in cats

Charisse S. Tietjen, Jeffrey R. Kirsch, Nathalie Clavier, Richard J. Traystman

Research output: Contribution to journalArticle

3 Scopus citations


Background and PurposeOxotremorine (OXO) is a cholinergic agonist that increases cerebral blood flow (CBF) when administered intravenously. We tested the hypothesis that OXO causes a dose-related increase in CBF in cats via a muscarinic mechanism that involves stimulation of nitric oxide synthase.

Original languageEnglish (US)
Pages (from-to)2160-2165
Number of pages6
Issue number11
StatePublished - Nov 1995


ASJC Scopus subject areas

  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing

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