Thrombotic microangiopathies

    Research output: Chapter in Book/Report/Conference proceedingChapter


    The thrombotic microangiopathies (TMs) are a group of diseases that share the qualities of thrombocytopenia and microangiopathic hemolytic anemia resulting in microvascular occlusion and end-organ damage. The classic TMs are thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). Since the early days of transplantation, it has been noted many patients developed a TM-type disease that was often fulminant and fatal. Research has been difficult due to lack of standardization of diagnostic criteria, and much controversy remains about the best therapy.

    Original languageEnglish (US)
    Title of host publicationBlood and Marrow Transplant Handbook
    Subtitle of host publicationComprehensive Guide for Patient Care
    PublisherSpringer New York
    Number of pages4
    ISBN (Print)9781441975058
    StatePublished - Dec 1 2011

    ASJC Scopus subject areas

    • Medicine(all)


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