TY - GEN
T1 - Thrombogenicity of poly(Vinyl) alcohol hydrogels is dependent on the crosslinking agent
AU - Cristina Puy, Novella M.Bates
AU - McCarty, Owen J.T.
AU - Hinds, Monica T.
N1 - Publisher Copyright:
© 2019 Omnipress - All rights reserved.
PY - 2019
Y1 - 2019
N2 - Statement of Purpose: Crosslinked poly(vinyl alcohol) (PVA) is a promising biomaterial for cardiovascular applications, particularly vascular grafts, due to its biocompatibility. It is currently used in medical applications for contact lenses, wound dressings, and catheters. Crosslinking methods of PVA include chemical and physical processes, which can potentially change the bulk and/or surface properties of the material. These material properties are critical for the success of implanted biomaterials. Specifically, an important consideration for vascular graft biomaterials is engineering these blood contacting materials to reduce or eliminate the potential for a thrombus formation. Thus, the goal of this study was to determine the role of the PVA crosslinking method on the material thrombogenicity.
AB - Statement of Purpose: Crosslinked poly(vinyl alcohol) (PVA) is a promising biomaterial for cardiovascular applications, particularly vascular grafts, due to its biocompatibility. It is currently used in medical applications for contact lenses, wound dressings, and catheters. Crosslinking methods of PVA include chemical and physical processes, which can potentially change the bulk and/or surface properties of the material. These material properties are critical for the success of implanted biomaterials. Specifically, an important consideration for vascular graft biomaterials is engineering these blood contacting materials to reduce or eliminate the potential for a thrombus formation. Thus, the goal of this study was to determine the role of the PVA crosslinking method on the material thrombogenicity.
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M3 - Conference contribution
AN - SCOPUS:85065399153
T3 - Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
SP - 469
BT - Society for Biomaterials Annual Meeting and Exposition 2019
PB - Society for Biomaterials
T2 - 42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
Y2 - 3 April 2019 through 6 April 2019
ER -