Thrombogenicity of poly(Vinyl) alcohol hydrogels is dependent on the crosslinking agent

Novella M.Bates Cristina Puy, Owen McCarty, Monica Hinds

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Statement of Purpose: Crosslinked poly(vinyl alcohol) (PVA) is a promising biomaterial for cardiovascular applications, particularly vascular grafts, due to its biocompatibility. It is currently used in medical applications for contact lenses, wound dressings, and catheters. Crosslinking methods of PVA include chemical and physical processes, which can potentially change the bulk and/or surface properties of the material. These material properties are critical for the success of implanted biomaterials. Specifically, an important consideration for vascular graft biomaterials is engineering these blood contacting materials to reduce or eliminate the potential for a thrombus formation. Thus, the goal of this study was to determine the role of the PVA crosslinking method on the material thrombogenicity.

Original languageEnglish (US)
Title of host publicationSociety for Biomaterials Annual Meeting and Exposition 2019
Subtitle of host publicationThe Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting
PublisherSociety for Biomaterials
Number of pages1
ISBN (Electronic)9781510883901
StatePublished - Jan 1 2019
Event42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Seattle, United States
Duration: Apr 3 2019Apr 6 2019

Publication series

NameTransactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium
Volume40
ISSN (Print)1526-7547

Conference

Conference42nd Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence
CountryUnited States
CitySeattle
Period4/3/194/6/19

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ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Biotechnology
  • Biomaterials
  • Materials Chemistry

Cite this

Cristina Puy, N. M. B., McCarty, O., & Hinds, M. (2019). Thrombogenicity of poly(Vinyl) alcohol hydrogels is dependent on the crosslinking agent. In Society for Biomaterials Annual Meeting and Exposition 2019: The Pinnacle of Biomaterials Innovation and Excellence - Transactions of the 42nd Annual Meeting (Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium; Vol. 40). Society for Biomaterials.