Thromboelastography profiles for controlled circulatory death donors: Validating the role of heparin

W. Christian Crannell; Mitch Sally; Keeley McConnell; Chris Connelly; Erin Maynard; Elizabeth Dewey; Peter Abt; C. Kristian Enestvedt

doi:10.1111/ctr.14518

Thromboelastography profiles for controlled circulatory death donors: Validating the role of heparin

W. Christian Crannell, Mitch Sally, Keeley McConnell, Chris Connelly, Erin Maynard, Elizabeth Dewey, Peter Abt, C. Kristian Enestvedt

Research output: Contribution to journal › Article › peer-review

Abstract

Controlled donation after circulatory death (cDCD) liver transplants are associated with increased ischemic-type biliary complications. Microvascular thrombosis secondary to decreased donor fibrinolysis may contribute to bile duct injury. We hypothesized that cDCD donors are hypercoagulable with impaired fibrinolysis and aim to use thromboelastography to characterize cDCD coagulation profiles.

Original language	English (US)
Article number	e14518
Journal	Clinical Transplantation
Volume	36
Issue number	2
DOIs	https://doi.org/10.1111/ctr.14518
State	Published - Feb 2022

ASJC Scopus subject areas

Transplantation

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10.1111/ctr.14518

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title = "Thromboelastography profiles for controlled circulatory death donors: Validating the role of heparin",

abstract = "Controlled donation after circulatory death (cDCD) liver transplants are associated with increased ischemic-type biliary complications. Microvascular thrombosis secondary to decreased donor fibrinolysis may contribute to bile duct injury. We hypothesized that cDCD donors are hypercoagulable with impaired fibrinolysis and aim to use thromboelastography to characterize cDCD coagulation profiles.",

author = "Crannell, {W. Christian} and Mitch Sally and Keeley McConnell and Chris Connelly and Erin Maynard and Elizabeth Dewey and Peter Abt and Enestvedt, {C. Kristian}",

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AU - Crannell, W. Christian

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AU - McConnell, Keeley

AU - Connelly, Chris

AU - Maynard, Erin

AU - Dewey, Elizabeth

AU - Abt, Peter

AU - Enestvedt, C. Kristian

PY - 2022/2

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N2 - Controlled donation after circulatory death (cDCD) liver transplants are associated with increased ischemic-type biliary complications. Microvascular thrombosis secondary to decreased donor fibrinolysis may contribute to bile duct injury. We hypothesized that cDCD donors are hypercoagulable with impaired fibrinolysis and aim to use thromboelastography to characterize cDCD coagulation profiles.

AB - Controlled donation after circulatory death (cDCD) liver transplants are associated with increased ischemic-type biliary complications. Microvascular thrombosis secondary to decreased donor fibrinolysis may contribute to bile duct injury. We hypothesized that cDCD donors are hypercoagulable with impaired fibrinolysis and aim to use thromboelastography to characterize cDCD coagulation profiles.

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Thromboelastography profiles for controlled circulatory death donors: Validating the role of heparin

Abstract

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