Thrombocytopenia in critical care patients

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    Thrombocytopenia is a common laboratory finding In the intensive care unit (ICU) patient. Because the causes can range from laboratory artifact to life-threatening processes such as thrombotic thrombocytopenic purpura (TTP), identifying the cause of thrombocytopenia is important. In the evaluation of the thrombocytopenia patient, one should incorporate all clinical clues such as why the patient is in the hospital, medications the patient is on, and other abnormal laboratory findings. One should ensure that the patient does not suffer from heparin-Induced thrombocytopenia (HIT) or one of the thrombotic microangiopathies (TMs). HIT can present in any patient on heparin and requires specific testing and antithrombotic therapy. This cover a spectrum of disease ranging from TTP to pregnancy complications and can have a variety of presentations. Management of disseminated intravascular coagulation depends on the patient's condition and complication. Other causes of ICU thrombocytopenia include sepsis, medication side effects, post-transfusion purpura, catastrophic anti phospholipid antibody disease, and immune thrombocytopenia.

    Original languageEnglish (US)
    Pages (from-to)267-282
    Number of pages16
    JournalJournal of Intensive Care Medicine
    Volume17
    Issue number6
    DOIs
    StatePublished - Nov 2002

    Fingerprint

    Critical Care
    Thrombocytopenia
    Heparin
    Thrombotic Thrombocytopenic Purpura
    Intensive Care Units
    Thrombotic Microangiopathies
    Purpura
    Idiopathic Thrombocytopenic Purpura
    Pregnancy Complications
    Disseminated Intravascular Coagulation
    Artifacts
    Anti-Idiotypic Antibodies
    Phospholipids
    Sepsis

    Keywords

    • Disseminated intravascular coagulation
    • Heparin-induced thrombocytopenia
    • Intensive care unit
    • Platelet
    • Thrombocytopenia

    ASJC Scopus subject areas

    • Critical Care and Intensive Care Medicine

    Cite this

    Thrombocytopenia in critical care patients. / Deloughery, Thomas.

    In: Journal of Intensive Care Medicine, Vol. 17, No. 6, 11.2002, p. 267-282.

    Research output: Contribution to journalArticle

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    abstract = "Thrombocytopenia is a common laboratory finding In the intensive care unit (ICU) patient. Because the causes can range from laboratory artifact to life-threatening processes such as thrombotic thrombocytopenic purpura (TTP), identifying the cause of thrombocytopenia is important. In the evaluation of the thrombocytopenia patient, one should incorporate all clinical clues such as why the patient is in the hospital, medications the patient is on, and other abnormal laboratory findings. One should ensure that the patient does not suffer from heparin-Induced thrombocytopenia (HIT) or one of the thrombotic microangiopathies (TMs). HIT can present in any patient on heparin and requires specific testing and antithrombotic therapy. This cover a spectrum of disease ranging from TTP to pregnancy complications and can have a variety of presentations. Management of disseminated intravascular coagulation depends on the patient's condition and complication. Other causes of ICU thrombocytopenia include sepsis, medication side effects, post-transfusion purpura, catastrophic anti phospholipid antibody disease, and immune thrombocytopenia.",
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