Thrombocytopenia associated with sodium valproate treatment

Andreas N. Neophytides; John G. Nutt; Jules R. Lodish

doi:10.1002/ana.410050414

Thrombocytopenia associated with sodium valproate treatment

Andreas N. Neophytides, John G. Nutt, Jules R. Lodish

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Abstract

The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.

Original language	English (US)
Pages (from-to)	389-390
Number of pages	2
Journal	Annals of Neurology
Volume	5
Issue number	4
DOIs	https://doi.org/10.1002/ana.410050414
State	Published - Apr 1979
Externally published	Yes

ASJC Scopus subject areas

Neurology
Clinical Neurology

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title = "Thrombocytopenia associated with sodium valproate treatment",

abstract = "The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.",

author = "Neophytides, {Andreas N.} and Nutt, {John G.} and Lodish, {Jules R.}",

year = "1979",

month = apr,

doi = "10.1002/ana.410050414",

language = "English (US)",

volume = "5",

pages = "389--390",

journal = "Annals of Neurology",

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publisher = "John Wiley and Sons Inc.",

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T1 - Thrombocytopenia associated with sodium valproate treatment

AU - Neophytides, Andreas N.

AU - Nutt, John G.

AU - Lodish, Jules R.

PY - 1979/4

Y1 - 1979/4

N2 - The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.

AB - The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.

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DO - 10.1002/ana.410050414

M3 - Article

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VL - 5

SP - 389

EP - 390

JO - Annals of Neurology

JF - Annals of Neurology

IS - 4

ER -

Thrombocytopenia associated with sodium valproate treatment

Abstract

ASJC Scopus subject areas

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