Three-Dimensional Shape Analysis of Right Ventricular Remodeling in Repaired Tetralogy of Fallot†Conflict of interest: Dr. Sheehan is a founder and equity holder of VentriPoint, Inc., Seattle, Washington.

Florence H. Sheehan, Shuping Ge, G. Wesley Vick, Kara Urnes, William S. Kerwin, Edward L. Bolson, Taylor Chung, John P. Kovalchin, David Sahn, Michael Jerosch-Herold, Alan H. Stolpen

Research output: Contribution to journalArticle

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Abstract

Understanding of right ventricular (RV) remodeling is needed to elucidate the mechanism of RV dysfunction in the overloaded right ventricle, but is hampered by the chamber's complex shape. We imaged 15 patients with repaired tetralogy of Fallot (TOF) and 8 normal subjects by magnetic resonance imaging in long- and short-axis views. We reconstructed the right ventricles in 3 dimensions using the piecewise smooth subdivision surface method. Shape was analyzed from cross-sectional contours generated by intersecting the right ventricle with 20 planes evenly spaced from apex to tricuspid annulus. Patients with TOF had dilated right ventricles compared with normal (end-diastolic volume index 216 ± 99 vs 81 ± 16 ml/m2, p

Original languageEnglish (US)
Pages (from-to)107-113
Number of pages7
JournalAmerican Journal of Cardiology
Volume101
Issue number1
DOIs
StatePublished - Jan 1 2008

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Ventricular Remodeling
Heart Ventricles
Tetralogy of Fallot
Right Ventricular Dysfunction
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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Three-Dimensional Shape Analysis of Right Ventricular Remodeling in Repaired Tetralogy of Fallot†Conflict of interest : Dr. Sheehan is a founder and equity holder of VentriPoint, Inc., Seattle, Washington. / Sheehan, Florence H.; Ge, Shuping; Vick, G. Wesley; Urnes, Kara; Kerwin, William S.; Bolson, Edward L.; Chung, Taylor; Kovalchin, John P.; Sahn, David; Jerosch-Herold, Michael; Stolpen, Alan H.

In: American Journal of Cardiology, Vol. 101, No. 1, 01.01.2008, p. 107-113.

Research output: Contribution to journalArticle

Sheehan, Florence H. ; Ge, Shuping ; Vick, G. Wesley ; Urnes, Kara ; Kerwin, William S. ; Bolson, Edward L. ; Chung, Taylor ; Kovalchin, John P. ; Sahn, David ; Jerosch-Herold, Michael ; Stolpen, Alan H. / Three-Dimensional Shape Analysis of Right Ventricular Remodeling in Repaired Tetralogy of Fallot†Conflict of interest : Dr. Sheehan is a founder and equity holder of VentriPoint, Inc., Seattle, Washington. In: American Journal of Cardiology. 2008 ; Vol. 101, No. 1. pp. 107-113.
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