TY - JOUR
T1 - Three-column osteotomy for correction of cervical and cervicothoracic deformities
T2 - alignment changes and early complications in a multicenter prospective series of 23 patients
AU - ISSG
AU - Smith, Justin S.
AU - Shaffrey, Christopher I.
AU - Lafage, Renaud
AU - Lafage, Virginie
AU - Schwab, Frank J.
AU - Kim, Han Jo
AU - Scheer, Justin K.
AU - Protopsaltis, Themistocles
AU - Passias, Peter
AU - Mundis, Gregory
AU - Hart, Robert
AU - Neuman, Brian
AU - Klineberg, Eric
AU - Hostin, Richard
AU - Bess, Shay
AU - Deviren, Vedat
AU - Ames, Christopher P.
N1 - Publisher Copyright:
© 2017, Springer-Verlag Berlin Heidelberg.
PY - 2017/8/1
Y1 - 2017/8/1
N2 - Purpose: Three-column osteotomy (3CO), including pedicle subtraction osteotomy (PSO) and vertebral column resection (VCR), can provide powerful alignment correction for adult cervical deformity (ACD). Our objective was to assess alignment changes and early complications associated with 3CO for ACD. Methods: ACD patients treated with 3CO with minimum 90-day follow-up were identified from a prospectively collected multicenter ACD database. Complications within 90-days of surgery and pre- and postoperative radiographs were collected. Results: All 23 ACD patients treated with 3CO (14 PSO/9 VCR) had minimum 90-day follow-up (mean age 62.3 years, previous cervical/cervicothoracic instrumentation in 52.2% and thoracic/thoracolumbar instrumentation in 47.8%). The primary diagnosis was kyphosis in 91.3% and coronal deformity in 8.7%. The mean number of fusion levels was 12 (range 6–18). The most common 3CO levels were T1 (39.1%), T2 (30.4%) and T3 (21.7%). Eighteen (12 major/6 minor) complications affected 13 (56.5%) patients. The most common complications were neurologic deficit (17.4%), wound infection (8.7%), distal junctional kyphosis (DJK 8.7%), and cardiorespiratory failure (8.7%). Three (13.0%) patients required re-operation within 90-days (1 each for nerve root motor deficit, DJK, and implant pain/prominence). Cervical alignment improved significantly following 3CO, including cervical lordosis (−2.8° to −12.9°, p = 0.036), C2-7 sagittal vertical axis (64.6–42.3 mm, p < 0.001), and T1 slope minus cervical lordosis (46.4°–27.0°, p < 0.001). Conclusions: Among 23 ACD patients treated with 3CO, cervical alignment improved significantly following surgery. Thirteen (56.5%) patients had at least one complication. The most common complications were neurologic deficit, infection, DJK, and cardiorespiratory failure.
AB - Purpose: Three-column osteotomy (3CO), including pedicle subtraction osteotomy (PSO) and vertebral column resection (VCR), can provide powerful alignment correction for adult cervical deformity (ACD). Our objective was to assess alignment changes and early complications associated with 3CO for ACD. Methods: ACD patients treated with 3CO with minimum 90-day follow-up were identified from a prospectively collected multicenter ACD database. Complications within 90-days of surgery and pre- and postoperative radiographs were collected. Results: All 23 ACD patients treated with 3CO (14 PSO/9 VCR) had minimum 90-day follow-up (mean age 62.3 years, previous cervical/cervicothoracic instrumentation in 52.2% and thoracic/thoracolumbar instrumentation in 47.8%). The primary diagnosis was kyphosis in 91.3% and coronal deformity in 8.7%. The mean number of fusion levels was 12 (range 6–18). The most common 3CO levels were T1 (39.1%), T2 (30.4%) and T3 (21.7%). Eighteen (12 major/6 minor) complications affected 13 (56.5%) patients. The most common complications were neurologic deficit (17.4%), wound infection (8.7%), distal junctional kyphosis (DJK 8.7%), and cardiorespiratory failure (8.7%). Three (13.0%) patients required re-operation within 90-days (1 each for nerve root motor deficit, DJK, and implant pain/prominence). Cervical alignment improved significantly following 3CO, including cervical lordosis (−2.8° to −12.9°, p = 0.036), C2-7 sagittal vertical axis (64.6–42.3 mm, p < 0.001), and T1 slope minus cervical lordosis (46.4°–27.0°, p < 0.001). Conclusions: Among 23 ACD patients treated with 3CO, cervical alignment improved significantly following surgery. Thirteen (56.5%) patients had at least one complication. The most common complications were neurologic deficit, infection, DJK, and cardiorespiratory failure.
KW - Adult
KW - Cervical deformity
KW - Kyphosis
KW - Osteotomy
KW - Surgery
UR - http://www.scopus.com/inward/record.url?scp=85016630007&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85016630007&partnerID=8YFLogxK
U2 - 10.1007/s00586-017-5071-1
DO - 10.1007/s00586-017-5071-1
M3 - Article
C2 - 28361367
AN - SCOPUS:85016630007
SN - 0940-6719
VL - 26
SP - 2128
EP - 2137
JO - European Spine Journal
JF - European Spine Journal
IS - 8
ER -