@inproceedings{d07c5f81f1324ea7b13602086847edea,
title = "Thermal coagulation of tissues. Liver studies indicate a distribution of rate parameters, not a single rate parameter, describes the coagulation process",
abstract = "Application of kinetic theory to the process of irreversible thermal denaturation of a biomolecule describes the transformation from a native form A to a denatured form B using a temperature-dependent first-order rate constant, k, in units of s-1. Thermal coagulation in tissues involves irreversible aggregation of denatured biomolecules and may be treated with this simple single-parameter kinetic theory. We present studies in pig liver which document changes in optical scattering as a quantitative measure of coagulation. The results indicate that a distribution of k parameters, not a single k parameter, is needed to describe liver coagulation. The practical implications are that thermal coagulation of liver begins faster than and finishes slower than the predictions based on a single parameter process.",
author = "Jacques, {Steven L.} and Carl Newman and He, {Xiao Yan}",
note = "Copyright: Copyright 2004 Elsevier B.V., All rights reserved.; Winter Annual Meeting of the American Society of Mechanical Engineers ; Conference date: 01-12-1991 Through 06-12-1991",
year = "1991",
language = "English (US)",
isbn = "0791808785",
series = "American Society of Mechanical Engineers, Heat Transfer Division, (Publication) HTD",
publisher = "Publ by ASME",
pages = "71--73",
booktitle = "Advances in Biological Heat and Mass Transfer",
}