Therapeutic modulation of cerebral l-lysine metabolism in a mouse model for glutaric aciduria type I

Medicine & Life Sciences

• Glutaric Acidemia I 100%
• Lysine 59%
• Glutaryl-CoA Dehydrogenase 34%
• saccharopine 28%
• glutaric acid 23%
• Carnitine 22%
• glutarylcarnitine 18%
• allysine 17%
• Liver 12%
• Brain 11%
• 2-Aminoadipate Transaminase 10%
• L-pipecolate dehydrogenase 10%
• L-Aminoadipate-Semialdehyde Dehydrogenase 9%
• Therapeutics 9%
• Diet 9%
• ornithine transporter 9%
• 3-hydroxyglutaric acid 8%
• Arginine 8%
• Enzymes 7%
• Hydroxylysine 7%
• Ketoglutarate Dehydrogenase Complex 7%
• Clofibrate 6%
• Peroxisomes 5%
• Tryptophan 4%
• Blood-Brain Barrier 4%
• Newborn Infant 3%
• Animal Models 3%
• Pharmacology 3%
• Kidney 2%
• Serum 2%