The V 2 transition ratio: A new electrocardiographic criterion for distinguishing left from right ventricular outflow tract tachycardia origin

Brian P. Betensky, Robert E. Park, Francis E. Marchlinski, Matthew D. Hutchinson, Fermin C. Garcia, Sanjay Dixit, David J. Callans, Joshua M. Cooper, Rupa Bala, David Lin, Michael P. Riley, Edward P. Gerstenfeld

Research output: Contribution to journalArticle

131 Citations (Scopus)

Abstract

Objectives: We sought to develop electrocardiography (ECG) criteria for distinguishing left ventricular outflow tract (LVOT) from right ventricular outflow tract (RVOT) origin in patients with idiopathic outflow tract ventricular tachycardia (OTVT) and lead V 3 R/S transition. Background: Several ECG criteria have been proposed for differentiating left from right OTVT origin; ventricular tachycardias (VTs) with left bundle branch block and V 3 transition remain a challenge. Methods: We analyzed the surface ECG pattern of patients with OTVT with a precordial transition in lead V 3 who underwent successful catheter ablation. Sinus and VT QRS morphologies were measured in limb and precordial leads with electronic calipers. The V 2 and V 3 transition ratios were calculated by computing the percentage R-wave during VT (R/R+S) VT divided by the percentage R-wave in sinus rhythm (R/R+S) SR. Results: We retrospectively analyzed ECGs from 40 patients (mean age 44 ± 14 years, 21 female) with outflow tract premature ventricular contractions (PVCs)/VT. Patients with structural heart disease, paced rhythms, and bundle branch block during sinus rhythm were excluded. The V 2 transition ratio was significantly greater for LVOT PVCs compared with RVOT PVCs (1.27 ± 0.60 vs. 0.23 ± 0.16; p <0.001) and was the only independent predictor of LVOT origin. In 21 prospective cases, a V 2 transition ratio 2 transition ratio is a novel electrocardiographic measure that reliably distinguishes LVOT from RVOT origin in patients with lead V 3 precordial transition. This measure might be useful for counseling patients and planning an ablation strategy.

Original languageEnglish (US)
Pages (from-to)2255-2262
Number of pages8
JournalJournal of the American College of Cardiology
Volume57
Issue number22
DOIs
StatePublished - May 31 2011
Externally publishedYes

Fingerprint

Ventricular Tachycardia
Tachycardia
Ventricular Premature Complexes
Electrocardiography
Bundle-Branch Block
Sinus Tachycardia
Catheter Ablation
Counseling
Heart Diseases
Extremities

Keywords

  • electrocardiogram
  • outflow tract
  • ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The V 2 transition ratio : A new electrocardiographic criterion for distinguishing left from right ventricular outflow tract tachycardia origin. / Betensky, Brian P.; Park, Robert E.; Marchlinski, Francis E.; Hutchinson, Matthew D.; Garcia, Fermin C.; Dixit, Sanjay; Callans, David J.; Cooper, Joshua M.; Bala, Rupa; Lin, David; Riley, Michael P.; Gerstenfeld, Edward P.

In: Journal of the American College of Cardiology, Vol. 57, No. 22, 31.05.2011, p. 2255-2262.

Research output: Contribution to journalArticle

Betensky, BP, Park, RE, Marchlinski, FE, Hutchinson, MD, Garcia, FC, Dixit, S, Callans, DJ, Cooper, JM, Bala, R, Lin, D, Riley, MP & Gerstenfeld, EP 2011, 'The V 2 transition ratio: A new electrocardiographic criterion for distinguishing left from right ventricular outflow tract tachycardia origin', Journal of the American College of Cardiology, vol. 57, no. 22, pp. 2255-2262. https://doi.org/10.1016/j.jacc.2011.01.035
Betensky, Brian P. ; Park, Robert E. ; Marchlinski, Francis E. ; Hutchinson, Matthew D. ; Garcia, Fermin C. ; Dixit, Sanjay ; Callans, David J. ; Cooper, Joshua M. ; Bala, Rupa ; Lin, David ; Riley, Michael P. ; Gerstenfeld, Edward P. / The V 2 transition ratio : A new electrocardiographic criterion for distinguishing left from right ventricular outflow tract tachycardia origin. In: Journal of the American College of Cardiology. 2011 ; Vol. 57, No. 22. pp. 2255-2262.
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AU - Betensky, Brian P.

AU - Park, Robert E.

AU - Marchlinski, Francis E.

AU - Hutchinson, Matthew D.

AU - Garcia, Fermin C.

AU - Dixit, Sanjay

AU - Callans, David J.

AU - Cooper, Joshua M.

AU - Bala, Rupa

AU - Lin, David

AU - Riley, Michael P.

AU - Gerstenfeld, Edward P.

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